ID   PHK16-0b
AC   CVCL_3123
SY   PHK160b
DR   BioSample; SAMN03470808
DR   JCRB; JCRB0141
DR   JCRB; NIHS0203
DR   Wikidata; Q54947361
RX   PubMed=1848315;
RX   PubMed=2173586;
CC   Population: Caucasian.
CC   Characteristics: Transfected with the plasmid pMHPV16d, which contains two copies of the complete HPV16 genome in a head-to-tail configuration (PubMed=1848315).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Discontinued: JCRB; NIHS0203; true.
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
ST   Source(s): JCRB=JCRB0141
ST   Amelogenin: X,Y
ST   CSF1PO: 12,13
ST   D13S317: 11
ST   D16S539: 11,12
ST   D5S818: 9,11
ST   D7S820: 9,11
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 16
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 15
//
RX   PubMed=1848315; DOI=10.1128/JVI.65.4.2000-2009.1991; PMCID=PMC240041;
RA   Yasumoto S., Taniguchi A., Sohma K.;
RT   "Epidermal growth factor (EGF) elicits down-regulation of human
RT   papillomavirus type 16 (HPV-16) E6/E7 mRNA at the transcriptional
RT   level in an EGF-stimulated human keratinocyte cell line: functional
RT   role of EGF-responsive silencer in the HPV-16 long control region.";
RL   J. Virol. 65:2000-2009(1991).
//
RX   PubMed=2173586; DOI=10.1016/0006-291x(90)90769-j;
RA   Hashida T., Yasumoto S.;
RT   "Casein kinase II activities related to hyperphosphorylation of human
RT   papillomavirus type 16-E7 oncoprotein in epidermal keratinocytes.";
RL   Biochem. Biophys. Res. Commun. 172:958-964(1990).
//