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Cellosaurus DT40-PTPN11(-/-) (CVCL_2G90)

[Text version]
Cell line name DT40-PTPN11(-/-)
Synonyms SHP2^(-) DT40; SHP-2-deficient DT40
Accession CVCL_2G90
Resource Identification Initiative To cite this cell line use: DT40-PTPN11(-/-) (RRID:CVCL_2G90)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; PTPN11.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Derived from sampling site: Cell type=B-cell.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_0249 (DT40)
Sex of cell Female
Age at sampling 1D
Category Cancer cell line

PubMed=9547347; DOI=10.1084/jem.187.8.1355
Maeda A., Kurosaki M., Ono M., Takai T., Kurosaki T.
Requirement of SH2-containing protein tyrosine phosphatases SHP-1 and SHP-2 for paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal.
J. Exp. Med. 187:1355-1360(1998)

Cell line collections RCB; RCB1502
Cell line databases/resources CLO; CLO_0051485
Encyclopedic resources Wikidata; Q54831509
Entry history
Entry creation22-Sep-2015
Last entry update21-Mar-2023
Version number8