ID   DT40-PTPN11(-/-)
AC   CVCL_2G90
SY   SHP2^(-) DT40; SHP-2-deficient DT40
DR   CLO; CLO_0051485
DR   RCB; RCB1502
DR   Wikidata; Q54831509
RX   PubMed=9547347;
CC   Group: Bird cell line.
CC   Knockout cell: Method=Targeted integration; UniProtKB; Q90687; PTPN11.
CC   Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
CC   Cell type: B-cell; CL=CL_0000236.
CC   Breed/subspecies: Hy-Line SC.
DI   NCIt; C134556; Chicken bursal lymphoma
OX   NCBI_TaxID=9031; ! Gallus gallus (Chicken)
HI   CVCL_0249 ! DT40
SX   Female
AG   1D
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 30-01-24; Version: 10
//
RX   PubMed=9547347; DOI=10.1084/jem.187.8.1355;
RA   Maeda A., Kurosaki M., Ono M., Takai T., Kurosaki T.;
RT   "Requirement of SH2-containing protein tyrosine phosphatases SHP-1 and
RT   SHP-2 for paired immunoglobulin-like receptor B (PIR-B)-mediated
RT   inhibitory signal.";
RL   J. Exp. Med. 187:1355-1360(1998).
//