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Cellosaurus WI-38 VA13 subline 2RA (CVCL_2759)

[Text version]
Cell line name WI-38 VA13 subline 2RA
Synonyms WI 38 VA13 subline 2RA; WI 38 VA-13 subline 2RA; WI 38VA13 subline 2RA; WI-38 VA13 sub 2 RA; WI38-VA13 subline 2RA; WI38 VA13/2RA; WI38VA13/2RA; VA13 2RA; WI-38 VA13; WI 38 VA 13; WI38-VA13; WI38/VA13; WI38VA13; VA-13; VA13; AG07217; AG7217
Accession CVCL_2759
Resource Identification Initiative To cite this cell line use: WI-38 VA13 subline 2RA (RRID:CVCL_2759)
Comments Population: Caucasian; Swedish.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597.
Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0579 (WI-38)
Children:
CVCL_U971 (VA13-TS4)
Sex of cell Female
Age at sampling 16FW
Category Transformed cell line
STR profile Source(s): ATCC=CCL-75.1; CCRID; CLS=300421; JCRB=JCRB9057; KCLB=10075.1; PubMed=24116068; RCB=RCB0251

Markers:
AmelogeninX
CSF1PO10,12
D2S133819,25
D3S135816,17
D5S81810
D7S8209,11
D8S117914
D13S31711
D16S53911,12
D18S5116,18
D19S43313,16.2
D21S1130,30.2
FGA22,24
Penta D13
Penta E13,14
TH019.3
TPOX8
vWA19,20

Run an STR similarity search on this cell line
Publications

PubMed=4290661
Anthony Joseph Girardi, David Weinstein, Paul Sidney Moorhead;
SV40 transformation of human diploid cells. A parallel study of viral and karyologic parameters.
Ann. Med. Exp. Biol. Fenn. 44:242-254(1966)

PubMed=656543; DOI=10.1016/S0006-3495(78)85487-3; PMCID=PMC1473442
Ursula Kristin Ehmann, Kem H. Cook, Errol Clive Friedberg;
The kinetics of thymine dimer excision in ultraviolet-irradiated human cells.
Biophys. J. 22:249-264(1978)

PubMed=699332; DOI=10.1016/0009-8981(78)90444-8
Gerd Knaup, Gerhard Pfleiderer, Klaus Bayreuther;
Human diploid lung fibroblast cell lines WI 26 and WI 38 exhibit isozyme shift of alkaline phosphatase after viral transformation.
Clin. Chim. Acta 88:375-383(1978)

PubMed=6256643; DOI=10.1038/288724a0
Rufus S. Day 3rd, Chuck H.J. Ziolkowski, Dominic A. Scudiero, Sharon A. Meyer, Anthony S. Lubiniecki, Anthony Joseph Girardi, Sheila Margaret Galloway, Gaither D. Bynum;
Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains.
Nature 288:724-727(1980)

DOI=10.2307/1308677
Rufus S. Day 3rd;
Adenovirus: a probe for human cells deficient in DNA repair.
BioScience 31:807-813(1981)

PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222
Robert J. Hay, Carolyn D. Williams, Marvin L. Macy, Kantharajapura Subbegowda Lavappa;
Cultured cell lines for research on pulmonary physiology available through the American Type Culture Collection.
Am. Rev. Respir. Dis. 125:222-232(1982)

PubMed=6538202; DOI=10.1083/jcb.98.3.1133; PMCID=PMC2113122
Bruno Azzarone, Horacio Guillermo Suarez, Maria Cristina Mingari, Lorenzo Moretta, Anthony Stephen Fauci;
4F2 monoclonal antibody recognizes a surface antigen on spread human fibroblasts of embryonic but not of adult origin.
J. Cell Biol. 98:1133-1137(1984)

PubMed=3002148; DOI=10.1007/978-1-4684-7853-2_15
Toshiharu Matsumura, Masato Nagata, Ryuji Konishi, Makoto Goto;
Studies of SV40-infected Werner syndrome fibroblasts.
Adv. Exp. Med. Biol. 190:313-330(1985)

PubMed=3413074; DOI=10.1073/pnas.85.16.6042; PMCID=PMC281901
Olivia M. Pereira-Smith, James R. Smith;
Genetic analysis of indefinite division in human cells: identification of four complementation groups.
Proc. Natl. Acad. Sci. U.S.A. 85:6042-6046(1988)

PubMed=1702221; DOI=10.1073/pnas.87.24.9908; PMCID=PMC55283
Ichiro Satokata, Kiyoji Tanaka, Naoyuki Miura, Iwai Miyamoto, Yoshiaki Satoh, Seiji Kondo, Yoshio Okada;
Characterization of a splicing mutation in group A xeroderma pigmentosum.
Proc. Natl. Acad. Sci. U.S.A. 87:9908-9912(1990)

PubMed=1372102; DOI=10.1016/0921-8777(92)90080-M
Ichiro Satokata, Kiyoji Tanaka, Naoyuki Miura, Masashi Narita, Takashi Mimaki, Yoshiaki Satoh, Seiji Kondo, Yoshio Okada;
Three nonsense mutations responsible for group A xeroderma pigmentosum.
Mutat. Res. 273:193-202(1992)

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=9175740; DOI=10.1093/hmg/6.6.921
Tracy M. Bryan, Lidija Marusic, Silvia Bacchetti, Masayoshi Namba, Roger Robert Reddel;
The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit.
Hum. Mol. Genet. 6:921-926(1997)

PubMed=24116068; DOI=10.1371/journal.pone.0075692; PMCID=PMC3792989
Ralf Weiskirchen, Jorg Weimer, Steffen K. Meurer, Anja Kron, Barbara Seipel, Inga Vater, Norbert Arnold, Reiner Siebert, Lie-Ming Xu, Scott Laurence Friedman, Carsten Bergmann;
Genetic characteristics of the human hepatic stellate cell line LX-2.
PLoS ONE 8:e75692.1-e75692.9(2013)

Cross-references
Cell line collections (Providers) ATCC; CCL-75.1
BCRC; 60504
CCTCC; GDC0122
CLS; 300421
Coriell; AG07217
ECACC; 85062512
IZSLER; BS CL 91
JCRB; JCRB9057
KCLB; 10075.1
RCB; RCB0251
Cell line databases/resources CLO; CLO_0009597
CLO; CLO_0009598
CLO; CLO_0009599
CLO; CLO_0035575
CLO; CLO_0050044
CLDB; cl4711
CLDB; cl4712
CLDB; cl4713
CLDB; cl4714
cancercelllines; CVCL_2759
CCRID; 1101HUM-PUMC000390
CCRID; 4201HUM-CCTCC00122
TOKU-E; 3451
Anatomy/cell type resources BTO; BTO_0003066
Biological sample resources BioSample; SAMN03471286
Chemistry resources ChEMBL-Cells; CHEMBL3308010
ChEMBL-Targets; CHEMBL612807
PubChem_Cell_line; CVCL_2759
Encyclopedic resources Wikidata; Q54994032
Gene expression databases GEO; GSM784286
GEO; GSM3048734
GEO; GSM3048735
GEO; GSM3048736
GEO; GSM3048737
Polymorphism and mutation databases Progenetix; CVCL_2759
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number38