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Cellosaurus VA13-TS4 (CVCL_U971)

[Text version]

Cell line name VA13-TS4
Accession CVCL_U971
Resource Identification Initiative To cite this cell line use: VA13-TS4 (RRID:CVCL_U971)
Comments Population: Caucasian; Swedish.
Transfected with: HGNC; 220; ADAMTS4.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from sampling site: Fetal lung. Cell type=Fibroblast.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2759 (WI-38 VA13 subline 2RA)
Sex of cell Female
Age at sampling 16FW
Category Transformed cell line

PubMed=14701864; DOI=10.1074/jbc.M312100200
Gao G., Plaas A., Thompson V.P., Jin S., Zuo F., Sandy J.D.
ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1.
J. Biol. Chem. 279:10042-10051(2004)

Anatomy/cell type resources BTO; BTO:0003065
Encyclopedic resources Wikidata; Q54992647
Entry history
Entry creation16-Apr-2014
Last entry update17-Mar-2022
Version number8