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Cellosaurus VA13-TS4 (CVCL_U971)

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Cell line name VA13-TS4
Accession CVCL_U971
Resource Identification Initiative To cite this cell line use: VA13-TS4 (RRID:CVCL_U971)
Comments Population: Caucasian; Swedish.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:220; ADAMTS4.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597.
Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2759 (WI-38 VA13 subline 2RA)
Sex of cell Female
Age at sampling 16FW
Category Transformed cell line
Publications

PubMed=14701864; DOI=10.1074/jbc.M312100200
Gui Gao, Anna Plaas, Vivian P. Thompson, Sue Jin, Feng-Rong Zuo, John David Sandy;
ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1.
J. Biol. Chem. 279:10042-10051(2004)

Cross-references
Anatomy/cell type resources BTO; BTO_0003065
Encyclopedic resources Wikidata; Q54992647
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number12