Cellosaurus Shh Light II (CVCL_2721)
| Cell line name | Shh Light II |
|---|---|
| Synonyms | Shh-Light II; Shh Light 2; Shh LIGHT 2; Shh-LIGHT2; Shh Light2; Shh-Light2; Shh-L2 |
| Accession | CVCL_2721 |
| Resource Identification Initiative | To cite this cell line use: Shh Light II (RRID:CVCL_2721) |
| Comments | Characteristics: Useful for the quantitative assay of biologically active hedgehog proteins (PubMed=10984056). Characteristics: Transfected with a GLI-responsive firefly luciferase reporter as well as a constitutive (TK promoter driven) Renilla-luciferase reporter (PubMed=10984056). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Genetic integration: Method=Transfection; Gene=UniProtKB; P27652; Renilla reniformis renilla-type luciferase. Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922. Cell type: Fibroblast; CL=CL_0000057. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss. |
| Hierarchy | Parent: CVCL_0594 (NIH 3T3) |
| Sex of cell | Male |
| Age at sampling | Embryo |
| Category | Spontaneously immortalized cell line |
| Web pages | Info; IdeaConnection; -; https://www.ideaconnection.com/patents/6088-Shh-Light2-Cells.html Provider; JHTV; C04409; https://jhu.technologypublisher.com/technology/16328 |
| Publications | PubMed=10984056; DOI=10.1038/35023008 |
| Cross-references | |
| Cell line collections (Providers) | ATCC; CRL-2795 - Discontinued
ATCC; JHU-68 - Discontinued |
| Cell line databases/resources | CLO; CLO_0009010 |
| Chemistry resources | ChEMBL-Cells; CHEMBL3430863
ChEMBL-Targets; CHEMBL3430862 PubChem_Cell_line; CVCL_2721 |
| Encyclopedic resources | Wikidata; Q54953329 |
| Entry history | |
| Entry creation | 04-Apr-2012 |
| Last entry update | 14-Aug-2025 |
| Version number | 16 |