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Cellosaurus HMT-3522 S2 (CVCL_2500)

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Cell line name HMT-3522 S2
Synonyms HMT-3522-S2; HMT-3522S2; HMT3522S2; S2; S-2; HMT-3522/gt-1; gt-1; HMT-3522/growth-transformed-1
Accession CVCL_2500
Resource Identification Initiative To cite this cell line use: HMT-3522 S2 (RRID:CVCL_2500)
Comments Population: Caucasian.
Characteristics: Established from parent cell line by permanent ommission of EGF in culture medium.
Donor information: Established from a nontumorigenic fibrocystic breast lesion (from parent cell line).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Sequence variations
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6855 (HMT-3522)
Children:
CVCL_2501 (HMT-3522 T4-2)
Sex of cell Female
Age at sampling 50Y
Category Spontaneously immortalized cell line
STR profile Source(s): ECACC=98102211

Markers:
AmelogeninX
CSF1PO11,12
D5S8189,11
D7S8209
D13S31711
D16S53911,13
TH019,9.3
TPOX11
vWA14,17

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Publications

PubMed=7982476; DOI=10.1006/excr.1994.1355
Caroline Moyret, Mogens W. Madsen, Jeff Cooke, Per Briand, Charles Theillet;
Gradual selection of a cellular clone presenting a mutation at codon 179 of the p53 gene during establishment of the immortalized human breast epithelial cell line HMT-3522.
Exp. Cell Res. 215:380-385(1994)

PubMed=8616848
Per Briand, Kirsten Vang Nielsen, Mogens W. Madsen, Ole William Petersen;
Trisomy 7p and malignant transformation of human breast epithelial cells following epidermal growth factor withdrawal.
Cancer Res. 56:2039-2044(1996)

PubMed=18316601; DOI=10.1158/0008-5472.CAN-07-2225; PMCID=PMC2662716
Aylin Rizki, Valerie Marie Weaver, Sun-Young Lee, Gabriela I. Rozenberg, Koei Chin, Connie A. Myers, Jamie L. Bascom, Joni D. Mott, Jeremy R. Semeiks, Leslie Roy Grate, I. Saira Mian ...Show all 19 authors... , Alexander David Borowsky, Roy A. Jensen, Michael O. Idowu, Fan-Qing Chen, David J. Chen, Ole William Petersen, Joe W. Gray, Mina J. Bissell; Show fewer authors
A human breast cell model of preinvasive to invasive transition.
Cancer Res. 68:1378-1387(2008)

Cross-references
Cell line collections (Providers) ECACC; 98102211
Cell line databases/resources cancercelllines; CVCL_2500
Encyclopedic resources Wikidata; Q54889969
Polymorphism and mutation databases Cosmic; 889086
Cosmic; 1066170
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number20