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Cellosaurus COR-L23/CPR (CVCL_2007)

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Cell line name COR-L23/CPR
Synonyms COR-L 23/CPR; L23/CPR
Accession CVCL_2007
Resource Identification Initiative To cite this cell line use: COR-L23/CPR (RRID:CVCL_2007)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1139 (COR-L23)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): ECACC=96042336

Markers:
AmelogeninX
CSF1PO11
D5S81810,12
D7S8209
D13S31710,11
D16S53911,13
TH019
TPOX8
vWA19

Run an STR similarity search on this cell line
Publications

PubMed=1327513
Peter Roy Twentyman, Karen A. Wright, Prakash Mistry, Lloyd R. Kelland, Barry A. Murrer;
Sensitivity to novel platinum compounds of panels of human lung cancer cell lines with acquired and inherent resistance to cisplatin.
Cancer Res. 52:5674-5680(1992)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ECACC; 96042336
Cell line databases/resources CLO; CLO_0002583
CLDB; cl5053
cancercelllines; CVCL_2007
LINCS_LDP; LCL-1779
Encyclopedic resources Wikidata; Q54814272
Gene expression databases GEO; GSM827460
Polymorphism and mutation databases Progenetix; CVCL_2007
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26