ID   COR-L23/CPR
AC   CVCL_2007
SY   COR-L 23/CPR; L23/CPR
DR   CLO; CLO_0002583
DR   CLDB; cl5053
DR   cancercelllines; CVCL_2007
DR   ECACC; 96042336
DR   GEO; GSM827460
DR   LINCS_LDP; LCL-1779
DR   Progenetix; CVCL_2007
DR   Wikidata; Q54814272
RX   PubMed=1327513;
RX   PubMed=20215515;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): ECACC=96042336
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 10,11
ST   D16S539: 11,13
ST   D5S818: 10,12
ST   D7S820: 9
ST   TH01: 9
ST   TPOX: 8
ST   vWA: 19
DI   NCIt; C4450; Lung large cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1139 ! COR-L23
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 26
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=1327513;
RA   Twentyman, Peter Roy
RA   Wright, Karen A.
RA   Mistry, Prakash
RA   Kelland, Lloyd R.
RA   Murrer, Barry A.
RT   "Sensitivity to novel platinum compounds of panels of human lung
RT   cancer cell lines with acquired and inherent resistance to
RT   cisplatin.";
RL   Cancer Res. 52:5674-5680(1992).
//