| Cell line name |
HSB2/GS |
|---|
| Synonyms |
HSB2 / GS; HSB2 HHV6A (GS); HSB2/HHV6A |
|---|
| Accession |
CVCL_1Y12 |
|---|
| Resource Identification Initiative |
To cite this cell line use: HSB2/GS (RRID:CVCL_1Y12) |
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| Comments |
Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084. |
|---|
| Sequence variations |
- Gene fusion; HGNC; 10879; STIL + HGNC; 11556; TAL1; Name(s)=STIL-TAL1, SIL-TAL1, SIL-SCL (from parent cell line).
- Mutation; HGNC; 3430; ERBB2; Simple; p.Pro1175Arg (c.3524C>G); Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 3690; FGFR3; Simple; p.Tyr226His (c.676T>C); Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 3690; FGFR3; Simple; p.Arg621His (c.1862G>A); ClinVar=VCV000016355; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 7881; NOTCH1; Simple; p.Leu1600Pro (c.4799T>C); Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000040468; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 8979; PIK3R1; Simple; p.Thr454Ile (c.1361C>T); Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 8979; PIK3R1; Simple; p.Gln455Lys (c.1363C>A); Zygosity=Unspecified (from parent cell line).
|
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| Disease |
Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_1859 (CCRF-HSB-2) |
|---|
| Sex of cell |
Male |
|---|
| Age at sampling |
11Y |
|---|
| Category |
Cancer cell line |
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| Publications | PubMed=1653487; DOI=10.1016/0042-6822(91)90424-A
Ablashi D.V., Balachandran N., Josephs S.F., Hung C.L., Krueger G.R.F., Kramarsky B., Salahuddin S.Z., Gallo R.C.
Genomic polymorphism, growth properties, and immunologic variations in human herpesvirus-6 isolates.
Virology 184:545-552(1991) |
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| Cross-references |
|---|
| Cell line collections (Providers) |
HIVReagentProgram; ARP-350
|
|---|
| Cell line databases/resources |
cancercelllines; CVCL_1Y12
|
|---|
| Encyclopedic resources |
Wikidata; Q54896366
|
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| Entry history |
|---|
| Entry creation | 22-Sep-2015 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 14 |
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