ID   HSB2/GS
AC   CVCL_1Y12
SY   HSB2 / GS; HSB2 HHV6A (GS); HSB2/HHV6A
DR   BEI_Resources; ARP-350
DR   cancercelllines; CVCL_1Y12
DR   Wikidata; Q54896366
RX   PubMed=1653487;
CC   Population: Caucasian.
CC   Sequence variation: Gene fusion; HGNC; 10879; STIL + HGNC; 11556; TAL1; Name(s)=STIL-TAL1, SIL-TAL1, SIL-SCL (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 3430; ERBB2; Simple; p.Pro1175Arg (c.3524C>G); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 3690; FGFR3; Simple; p.Tyr226His (c.676T>C); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 3690; FGFR3; Simple; p.Arg621His (c.1862G>A); ClinVar=VCV000016355; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7881; NOTCH1; Simple; p.Leu1600Pro (c.4799T>C); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000040468; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8979; PIK3R1; Simple; p.Thr454Ile (c.1361C>T); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8979; PIK3R1; Simple; p.Gln455Lys (c.1363C>A); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1859 ! CCRF-HSB-2
SX   Male
AG   11Y
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 10-09-24; Version: 15
//
RX   PubMed=1653487; DOI=10.1016/0042-6822(91)90424-A;
RA   Ablashi D.V., Balachandran N., Josephs S.F., Hung C.-L.,
RA   Krueger G.R.F., Kramarsky B., Salahuddin S.Z., Gallo R.C.;
RT   "Genomic polymorphism, growth properties, and immunologic variations
RT   in human herpesvirus-6 isolates.";
RL   Virology 184:545-552(1991).
//