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Cellosaurus DT40-RASGRP1(-/-)-RASGRP3(-/-) (CVCL_1U39)

[Text version]
Cell line name DT40-RASGRP1(-/-)-RASGRP3(-/-)
Synonyms GRP1^(-)/GRP3^(-)DT40
Accession CVCL_1U39
Resource Identification Initiative To cite this cell line use: DT40-RASGRP1(-/-)-RASGRP3(-/-) (RRID:CVCL_1U39)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; RASGRP1+RASGRP3.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Derived from sampling site: Cell type=B-cell.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_0249 (DT40)
Sex of cell Female
Age at sampling 1D
Category Cancer cell line

PubMed=14676298; DOI=10.1084/jem.20031547
Oh-hora M., Johmura S., Hashimoto A., Hikida M., Kurosaki T.
Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling.
J. Exp. Med. 198:1841-1851(2003)

Cell line collections RCB; RCB1865
Cell line databases/resources CLO; CLO_0051511
Encyclopedic resources Wikidata; Q54831531
Entry history
Entry creation08-Jul-2015
Last entry update21-Mar-2023
Version number8