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Cellosaurus DT40-ATM(-/-) (CVCL_1T23)

[Text version]
Cell line name DT40-ATM(-/-)
Synonyms ATM-/- DT40; Delta-Atm-DT40
Accession CVCL_1T23
Resource Identification Initiative To cite this cell line use: DT40-ATM(-/-) (RRID:CVCL_1T23)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; ATM.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Derived from sampling site: Cell type=B-cell.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_0249 (DT40)
CVCL_1T24 (DT40-ATM(-/-)-XRCC6(-/-))
Sex of cell Female
Age at sampling 1D
Category Cancer cell line

PubMed=10597300; DOI=10.1038/sj.onc.1203172
Takao N., Kato H., Mori R., Morrison C., Sonoda E., Sun X., Shimizu H., Yoshioka K., Takeda S., Yamamoto K.-I.
Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation.
Oncogene 18:7002-7009(1999)

PubMed=10654944; DOI=10.1093/emboj/19.3.463
Morrison C., Sonoda E., Takao N., Shinohara A., Yamamoto K.-I., Takeda S.
The controlling role of ATM in homologous recombinational repair of DNA damage.
EMBO J. 19:463-471(2000)

Cell line collections RCB; RCB1649
Cell line databases/resources CLO; CLO_0051493
Encyclopedic resources Wikidata; Q54831469
Entry history
Entry creation08-Jul-2015
Last entry update21-Mar-2023
Version number8