ID   DT40-ATM(-/-)
AC   CVCL_1T23
SY   ATM-/- DT40; Delta-Atm-DT40
DR   CLO; CLO_0051493
DR   RCB; RCB1649
DR   Wikidata; Q54831469
RX   PubMed=10597300;
RX   PubMed=10654944;
CC   Group: Bird cell line.
CC   Knockout cell: Method=Targeted integration; ATM.
CC   Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
CC   Derived from sampling site: Cell type=B-cell.
CC   Breed/subspecies: Hy-Line SC.
DI   NCIt; C134556; Chicken bursal lymphoma
OX   NCBI_TaxID=9031; ! Gallus gallus (Chicken)
HI   CVCL_0249 ! DT40
SX   Female
AG   1D
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 21-03-23; Version: 8
RX   PubMed=10597300; DOI=10.1038/sj.onc.1203172;
RA   Takao N., Kato H., Mori R., Morrison C., Sonoda E., Sun X.,
RA   Shimizu H., Yoshioka K., Takeda S., Yamamoto K.-I.;
RT   "Disruption of ATM in p53-null cells causes multiple functional
RT   abnormalities in cellular response to ionizing radiation.";
RL   Oncogene 18:7002-7009(1999).
RX   PubMed=10654944; DOI=10.1093/emboj/19.3.463;
RA   Morrison C., Sonoda E., Takao N., Shinohara A., Yamamoto K.-I.,
RA   Takeda S.;
RT   "The controlling role of ATM in homologous recombinational repair of
RT   DNA damage.";
RL   EMBO J. 19:463-471(2000).