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Cellosaurus CMT27 (CVCL_1R41)

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Cell line name CMT27
Synonyms CMT-27; Canine Mammary Tumor 27
Accession CVCL_1R41
Resource Identification Initiative To cite this cell line use: CMT27 (RRID:CVCL_1R41)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 18 hours (PubMed=27257868).
Omics: Transcriptomics; Microarray.
Caution: On the basis of STR profile (PubMed=21908323; PubMed=27197945) CMT12 and CMT27 seem to originate from the same donor.
Disease Canine mammary carcinoma (NCIt: C124249)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Poodle; VBO=VBO_0201048.
Originate from same individual CVCL_L329 ! CMT12
Sex of cell Female
Age at sampling >10Y
Category Cancer cell line
STR profile Source(s): PubMed=27197945

Markers:
Dog FHC2010235
Dog FHC2054151
Dog FHC2079271
Dog PEZ1115
Dog PEZ12277
Dog PEZ20176
Dog PEZ3113,119
Dog PEZ5103
Dog PEZ6176
Dog PEZ8244,249

Run an STR similarity search on this cell line
Publications

PubMed=19130492; DOI=10.1002/jcb.22034
Patricia DeInnocentes, Payal Agarwal, R. Curtis Bird;
Phenotype-rescue of cyclin-dependent kinase inhibitor p16/INK4A defects in a spontaneous canine cell model of breast cancer.
J. Cell. Biochem. 106:491-505(2009)

PubMed=21908323; DOI=10.1177/1040638711408064
Liza E. O'Donoghue, Jason P. Rivest, Dawn L. Duval;
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

PubMed=23238983; DOI=10.1002/jcb.24476
Payal Agarwal, Maninder Sandey, Patricia DeInnocentes, R. Curtis Bird;
Tumor suppressor gene p16/INK4A/CDKN2A-dependent regulation into and out of the cell cycle in a spontaneous canine model of breast cancer.
J. Cell. Biochem. 114:1355-1363(2013)

PubMed=27257868; DOI=10.1371/journal.pone.0156689; PMCID=PMC4892608
Junko Maeda, Coral Eva Froning, Colleen A. Brents, Barbara J. Rose, Douglas H. Thamm, Takamitsu A. Kato;
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:e0156689.1-e0156689.18(2016)

PubMed=27197945; DOI=10.1111/vco.12192; PMCID=PMC5656225
Jared S. Fowles, Deanna D. Dailey, Daniel L. Gustafson, Douglas H. Thamm, Dawn L. Duval;
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

Cross-references
Encyclopedic resources Wikidata; Q54813853
Gene expression databases GEO; GSM1974784
Entry history
Entry creation08-Jul-2015
Last entry update10-Apr-2025
Version number13