ID   CMT27
AC   CVCL_1R41
SY   CMT-27; Canine Mammary Tumor 27
DR   GEO; GSM1974784
DR   Wikidata; Q54813853
RX   PubMed=19130492;
RX   PubMed=21908323;
RX   PubMed=23238983;
RX   PubMed=27197945;
RX   PubMed=27257868;
CC   Part of: FACC canine tumor cell line panel.
CC   Doubling time: 18 hours (PubMed=27257868).
CC   Omics: Transcriptome analysis by microarray.
CC   Caution: On the basis of STR profile (PubMed=21908323; PubMed=27197945) CMT12 and CMT27 seem to originate from the same donor.
CC   Breed/subspecies: Poodle.
ST   Source(s): PubMed=27197945
ST   Dog FHC2010: 235
ST   Dog FHC2054: 151
ST   Dog FHC2079: 271
ST   Dog PEZ1: 115
ST   Dog PEZ3: 113,119
ST   Dog PEZ5: 103
ST   Dog PEZ6: 176
ST   Dog PEZ8: 244,249
ST   Dog PEZ12: 277
ST   Dog PEZ20: 176
DI   NCIt; C124249; Canine mammary carcinoma
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
OI   CVCL_L329 ! CMT12
SX   Female
AG   >10Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 21-03-23; Version: 11
RX   PubMed=19130492; DOI=10.1002/jcb.22034;
RA   DeInnocentes P., Agarwal P., Bird R.C.;
RT   "Phenotype-rescue of cyclin-dependent kinase inhibitor p16/INK4A
RT   defects in a spontaneous canine cell model of breast cancer.";
RL   J. Cell. Biochem. 106:491-505(2009).
RX   PubMed=21908323; DOI=10.1177/1040638711408064;
RA   O'Donoghue L.E., Rivest J.P., Duval D.L.;
RT   "Polymerase chain reaction-based species verification and
RT   microsatellite analysis for canine cell line validation.";
RL   J. Vet. Diagn. Invest. 23:780-785(2011).
RX   PubMed=23238983; DOI=10.1002/jcb.24476;
RA   Agarwal P., Sandey M., DeInnocentes P., Bird R.C.;
RT   "Tumor suppressor gene p16/INK4A/CDKN2A-dependent regulation into and
RT   out of the cell cycle in a spontaneous canine model of breast
RT   cancer.";
RL   J. Cell. Biochem. 114:1355-1363(2013).
RX   PubMed=27197945; DOI=10.1111/vco.12192;
RA   Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.;
RT   "The Flint Animal Cancer Center (FACC) canine tumour cell line panel:
RT   a resource for veterinary drug discovery, comparative oncology and
RT   translational medicine.";
RL   Vet. Comp. Oncol. 15:481-492(2017).
RX   PubMed=27257868; DOI=10.1371/journal.pone.0156689;
RA   Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.;
RT   "Intrinsic radiosensitivity and cellular characterization of 27 canine
RT   cancer cell lines.";
RL   PLoS ONE 11:E0156689-E0156689(2016).