• Mutation; VGNC; 42490; KMT2C; Simple; p.Arg1201fs (c.3600delGinsAA); Zygosity=Homozygous (PubMed=31175136).
  
• Mutation; VGNC; 47719; TP53; Simple; p.Val132Glu (c.395T>A); Zygosity=Homozygous (PubMed=31175136).
  

PubMed=3462415; DOI=10.1093/jnci/77.3.783
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Biologic properties of cell lines derived from canine mammary carcinomas.
J. Natl. Cancer Inst. 77:783-792(1986)

CLPUB00711
Sartin E.A.
Biological properties of canine mammary tumors and cell lines.
Thesis PhD (1990), Auburn University College of Veterinary Medicine, United States

PubMed=8476218
Sartin E.A., Barnes S., Toivio-Kinnucan M., Wright J.C., Wolfe L.G.
Heterogenic properties of clonal cell lines derived from canine mammary carcinomas and sensitivity to tamoxifen and doxorubicin.
Anticancer Res. 13:229-236(1993)

PubMed=11848473
Vatne V., Litlekalsoey J., Thorsen F., Ness G.O., Wentzel-Larsen T., Hostmark J.G.
Characterization of cell lines originating from an invasive transitional cell carcinoma.
Anticancer Res. 21:3199-3207(2001)

PubMed=12529965
Whitley E.M., Sellins K.S., Ewald S.J., Smith B.F., Yang S.-M., Sartin E.A., Wolfe L.G.
Canine mammary tumor cells transfected with B7-1 or B7-2 stimulate proliferation of peripheral blood mononuclear cells.
Anticancer Res. 22:2567-2574(2002)

PubMed=19130492; DOI=10.1002/jcb.22034
DeInnocentes P., Agarwal P., Bird R.C.
Phenotype-rescue of cyclin-dependent kinase inhibitor p16/INK4A defects in a spontaneous canine cell model of breast cancer.
J. Cell. Biochem. 106:491-505(2009)

PubMed=21801068; DOI=10.2460/ajvr.72.8.1097
Stokol T., Daddona J.L., Mubayed L.S., Trimpert J., Kang S.
Evaluation of tissue factor expression in canine tumor cells.
Am. J. Vet. Res. 72:1097-1106(2011)

PubMed=21908323; DOI=10.1177/1040638711408064
O'Donoghue L.E., Rivest J.P., Duval D.L.
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

PubMed=23238983; DOI=10.1002/jcb.24476
Agarwal P., Sandey M., DeInnocentes P., Bird R.C.
Tumor suppressor gene p16/INK4A/CDKN2A-dependent regulation into and out of the cell cycle in a spontaneous canine model of breast cancer.
J. Cell. Biochem. 114:1355-1363(2013)

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=27197945; DOI=10.1111/vco.12192
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)