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Cellosaurus NP-3 (CVCL_1R16)

[Text version]
Cell line name NP-3
Synonyms NP 3; Case 2; NB3972
Accession CVCL_1R16
Resource Identification Initiative To cite this cell line use: NP-3 (RRID:CVCL_1R16)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 36 hours, at 129th passage (CelloPub=CLPUB00260).
Derived from sampling site: Brain; left frontal lobe.
Sequence variations
  • Mutation; HGNC; 9588; PTEN; Simple; p.Met199del (c.592_594ATG[1]) (c.595_597delATG); ClinVar=VCV000418437; Zygosity=Unspecified (PubMed=10551321).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): DepMap; JCRB

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135815,16
D5S8189,10
D7S82010
D8S117914
D13S31713
D16S53911
D18S5123
D21S1132.2
FGA20,22
Penta D13
Penta E16
TH017,9
TPOX9,11
vWA17,19

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Publications

CLPUB00260
Yamazaki K.
Tumorigenicity of established human glioma cell lines in lasat and nude mice.
Neuropathology 3:29-38(1982)

PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x
Zhang S., Endo S., Koga H., Ichikawa T., Feng X., Onda K., Washiyama K., Kumanishi T.
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations.
Jpn. J. Cancer Res. 87:900-907(1996)

PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x
Zhang S.J., Endo S., Ichikawa T., Yoshimura J., Onda K., Tanaka R., Washiyama K., Kumanishi T.
Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.
Jpn. J. Cancer Res. 90:934-941(1999)

PubMed=18415661; DOI=10.1007/s10014-007-0226-0
Tanaka Y., Zhang S.-J., Terasaki H., Koga H., Endo S., Usui H., Washiyama K., Kumanishi T., Uematsu Y., Itakura T.
Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines.
Brain Tumor Pathol. 25:9-17(2008)

Cross-references
Cell line collections JCRB; JCRB1567
RCB; RCB4504
Cell line databases/resources Cell_Model_Passport; SIDM01847
DepMap; ACH-001609
Encyclopedic resources Wikidata; Q54930957
Entry history
Entry creation08-Jul-2015
Last entry update16-Dec-2021
Version number11