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Cellosaurus NP-3 (CVCL_1R16)

[Text version]
Cell line name NP-3
Synonyms NP 3; Case 2; NB3972
Accession CVCL_1R16
Resource Identification Initiative To cite this cell line use: NP-3 (RRID:CVCL_1R16)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 36 hours (Note=At 129th passage) (CelloPub=CLPUB00260).
Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Met199del (c.592_594ATG[1]) (c.595_597delATG); ClinVar=VCV000418437; Zygosity=Unspecified (PubMed=10551321).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001609; JCRB=JCRB1567

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135815,16
D5S8189,10
D7S82010
D8S117914
D13S31713
D16S53911
D18S5123
D21S1132.2
FGA20,22
Penta D13
Penta E16
TH017,9
TPOX9,11
vWA17,19

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Publications

CLPUB00260
Kazunori Yamazaki;
Tumorigenicity of established human glioma cell lines in lasat and nude mice.
Neuropathology 3:29-38(1982)

PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x; PMCID=PMC5921198
Shu-Jing Zhang, Sumio Endo, Hisashi Koga, Tomio Ichikawa, Xue-Lian Feng, Kiyoshi Onda, Kazuo Washiyama, Toshiro Kumanishi;
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations.
Jpn. J. Cancer Res. 87:900-907(1996)

PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x; PMCID=PMC5926156
Shu-Jing Zhang, Sumio Endo, Tomio Ichikawa, Jun-ichi Yoshimura, Kiyoshi Onda, Ryuichi Tanaka, Kazuo Washiyama, Toshiro Kumanishi;
Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.
Jpn. J. Cancer Res. 90:934-941(1999)

PubMed=18415661; DOI=10.1007/s10014-007-0226-0
Yoshiyuki Tanaka, Shu-Jing Zhang, Hiroshi Terasaki, Hisashi Koga, Sumio Endo, Hiroshi Usui, Kazuo Washiyama, Toshiro Kumanishi, Yuji Uematsu, Toru Itakura;
Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines.
Brain Tumor Pathol. 25:9-17(2008)

Cross-references
Cell line collections (Providers) JCRB; JCRB1567
RCB; RCB4504
Cell line databases/resources cancercelllines; CVCL_1R16
Cell_Model_Passport; SIDM01847
DepMap; ACH-001609
Encyclopedic resources Wikidata; Q54930957
Entry history
Entry creation08-Jul-2015
Last entry update19-Dec-2024
Version number16