ID   NP-3
AC   CVCL_1R16
SY   NP 3; Case 2; NB3972
DR   cancercelllines; CVCL_1R16
DR   Cell_Model_Passport; SIDM01847
DR   DepMap; ACH-001609
DR   JCRB; JCRB1567
DR   RCB; RCB4504
DR   Wikidata; Q54930957
RX   CelloPub=CLPUB00260;
RX   PubMed=8878451;
RX   PubMed=10551321;
RX   PubMed=18415661;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Doubling time: 36 hours (Note=At 129th passage) (CelloPub=CLPUB00260).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Met199del (c.592_594ATG[1]) (c.595_597delATG); ClinVar=VCV000418437; Zygosity=Unspecified (PubMed=10551321).
CC   Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
ST   Source(s): DepMap; JCRB
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 13
ST   D16S539: 11
ST   D18S51: 23
ST   D21S11: 32.2
ST   D3S1358: 15,16
ST   D5S818: 9,10
ST   D7S820: 10
ST   D8S1179: 14
ST   FGA: 20,22
ST   Penta D: 13
ST   Penta E: 16
ST   TH01: 7,9
ST   TPOX: 9,11
ST   vWA: 17,19
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   64Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 05-10-23; Version: 14
//
RX   CelloPub=CLPUB00260;
RA   Yamazaki K.;
RT   "Tumorigenicity of established human glioma cell lines in lasat and
RT   nude mice.";
RL   Neuropathology 3:29-38(1982).
//
RX   PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x;
RA   Zhang S., Endo S., Koga H., Ichikawa T., Feng X., Onda K.,
RA   Washiyama K., Kumanishi T.;
RT   "A comparative study of glioma cell lines for p16, p15, p53 and p21
RT   gene alterations.";
RL   Jpn. J. Cancer Res. 87:900-907(1996).
//
RX   PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x;
RA   Zhang S.-J., Endo S., Ichikawa T., Yoshimura J., Onda K., Tanaka R.,
RA   Washiyama K., Kumanishi T.;
RT   "Rare-type mutations of MMAC1 tumor suppressor gene in human glioma
RT   cell lines and their tumors of origin.";
RL   Jpn. J. Cancer Res. 90:934-941(1999).
//
RX   PubMed=18415661; DOI=10.1007/s10014-007-0226-0;
RA   Tanaka Y., Zhang S.-J., Terasaki H., Koga H., Endo S., Usui H.,
RA   Washiyama K., Kumanishi T., Uematsu Y., Itakura T.;
RT   "Frequent and variable abnormalities in p14 tumor suppressor gene in
RT   glioma cell lines.";
RL   Brain Tumor Pathol. 25:9-17(2008).
//