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Cellosaurus HROC32 T3 M1 (CVCL_1D07)

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Cell line name HROC32 T3 M1
Synonyms HROC32X
Accession CVCL_1D07
Resource Identification Initiative To cite this cell line use: HROC32 T3 M1 (RRID:CVCL_1D07)
Comments From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
Population: Caucasian.
Characteristics: Established from a patient-derived xenograft established in female NOD SCID mice.
Doubling time: 33.8 +- 5.4 hours (PubMed=25574089).
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ala (c.35G>C); ClinVar=VCV000045122; Zygosity=Unspecified (CLS=300819).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (CLS=300819).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_YD55 ! B-LCL-HROC32
CVCL_1D06 ! HROC32
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
STR profile Source(s): CLS=300819

Markers:
AmelogeninX
CSF1PO14
D5S81811,12
D7S8208,11
D13S31711,12
D16S53911,12
D21S1131
TH018,9
TPOX8,11
vWA19

Run an STR similarity search on this cell line
Publications

PubMed=25574089; DOI=10.3748/wjg.v21.i1.164; PMCID=PMC4284332
Claudia Maletzki, Michael Gock, Martin Randow, Ernst Klar, Maja Huhns, Friedrich Prall, Michael Linnebacher;
Establishment and characterization of cell lines from chromosomal instable colorectal cancer.
World J. Gastroenterol. 21:164-176(2015)

PubMed=31601052; DOI=10.3390/cancers11101520; PMCID=PMC6826890
Christina Susanne Mullins, Bianca Micheel, Stephanie Matschos, Matthias Leuchter, Florian Burtin, Mathias Krohn, Maja Huhns, Ernst Klar, Friedrich Prall, Michael Linnebacher;
Integrated biobanking and tumor model establishment of human colorectal carcinoma provides excellent tools for preclinical research.
Cancers (Basel) 11:1520.1-1520.18(2019)

Cross-references
Cell line collections (Providers) CLS; 300819
Cell line databases/resources cancercelllines; CVCL_1D07
Encyclopedic resources Wikidata; Q54895284
Polymorphism and mutation databases Cosmic; 2324291
Entry history
Entry creation08-Jul-2015
Last entry update19-Dec-2024
Version number19