ID   HROC32 T3 M1
AC   CVCL_1D07
SY   HROC32X
DR   cancercelllines; CVCL_1D07
DR   CLS; 300819
DR   Cosmic; 2324291
DR   Wikidata; Q54895284
RX   PubMed=25574089;
RX   PubMed=31601052;
CC   From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
CC   Population: Caucasian.
CC   Characteristics: Established from a patient-derived xenograft established in female NOD SCID mice.
CC   Doubling time: 33.8 +- 5.4 hours (PubMed=25574089).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ala (c.35G>C); ClinVar=VCV000045122; Zygosity=Unspecified (CLS=300819).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (CLS=300819).
CC   Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
ST   Source(s): CLS=300819
ST   Amelogenin: X
ST   CSF1PO: 14
ST   D13S317: 11,12
ST   D16S539: 11,12
ST   D21S11: 31
ST   D5S818: 11,12
ST   D7S820: 8,11
ST   TH01: 8,9
ST   TPOX: 8,11
ST   vWA: 19
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_YD55 ! B-LCL-HROC32
OI   CVCL_1D06 ! HROC32
SX   Female
AG   82Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 19-12-24; Version: 19
//
RX   PubMed=31601052; DOI=10.3390/cancers11101520; PMCID=PMC6826890;
RA   Mullins, Christina Susanne
RA   Micheel, Bianca
RA   Matschos, Stephanie
RA   Leuchter, Matthias
RA   Burtin, Florian
RA   Krohn, Mathias
RA   Huhns, Maja
RA   Klar, Ernst
RA   Prall, Friedrich
RA   Linnebacher, Michael
RT   "Integrated biobanking and tumor model establishment of human
RT   colorectal carcinoma provides excellent tools for preclinical
RT   research.";
RL   Cancers (Basel) 11:1520.1-1520.18(2019).
//
RX   PubMed=25574089; DOI=10.3748/wjg.v21.i1.164; PMCID=PMC4284332;
RA   Maletzki, Claudia
RA   Gock, Michael
RA   Randow, Martin
RA   Klar, Ernst
RA   Huhns, Maja
RA   Prall, Friedrich
RA   Linnebacher, Michael
RT   "Establishment and characterization of cell lines from chromosomal
RT   instable colorectal cancer.";
RL   World J. Gastroenterol. 21:164-176(2015).
//