ID   HROC32 T3 M1
AC   CVCL_1D07
SY   HROC32X
DR   cancercelllines; CVCL_1D07
DR   CLS; 300819
DR   Cosmic; 2324291
DR   Wikidata; Q54895284
RX   PubMed=25574089;
RX   PubMed=31601052;
CC   From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
CC   Population: Caucasian.
CC   Characteristics: Established from a patient-derived xenograft established in female NOD SCID mice.
CC   Doubling time: 33.8 +- 5.4 hours (PubMed=25574089).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ala (c.35G>C); ClinVar=VCV000045122; Zygosity=Unspecified (CLS=300819).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (CLS=300819).
CC   Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
ST   Source(s): CLS=300819
ST   Amelogenin: X
ST   CSF1PO: 14
ST   D13S317: 11,12
ST   D16S539: 11,12
ST   D21S11: 31
ST   D5S818: 11,12
ST   D7S820: 8,11
ST   TH01: 8,9
ST   TPOX: 8,11
ST   vWA: 19
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_YD55 ! B-LCL-HROC32
OI   CVCL_1D06 ! HROC32
SX   Female
AG   82Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 19-12-24; Version: 19
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RX   PubMed=25574089; DOI=10.3748/wjg.v21.i1.164; PMCID=PMC4284332;
RA   Maletzki C., Gock M., Randow M., Klar E., Huhns M., Prall F.,
RA   Linnebacher M.;
RT   "Establishment and characterization of cell lines from chromosomal
RT   instable colorectal cancer.";
RL   World J. Gastroenterol. 21:164-176(2015).
//
RX   PubMed=31601052; DOI=10.3390/cancers11101520; PMCID=PMC6826890;
RA   Mullins C.S., Micheel B., Matschos S., Leuchter M., Burtin F.,
RA   Krohn M., Huhns M., Klar E., Prall F., Linnebacher M.;
RT   "Integrated biobanking and tumor model establishment of human
RT   colorectal carcinoma provides excellent tools for preclinical
RT   research.";
RL   Cancers (Basel) 11:1520.1-1520.18(2019).
//