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Cellosaurus Ku812E (CVCL_0615)

[Text version]
Cell line name Ku812E
Synonyms KU812E; KU-812E; KU 812E
Accession CVCL_0615
Resource Identification Initiative To cite this cell line use: Ku812E (RRID:CVCL_0615)
Comments Population: Japanese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Basophil progenitor cell; CL=CL_0000613.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Arg (c.395A>G); ClinVar=VCV000376625; Zygosity=Homozygous (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0379 (Ku812)
Sex of cell Male
Age at sampling 38Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2100; CCRID=1102HUM-NIFDC00110; JCRB=JCRB0104.1; RCB=RCB0496

Markers:
AmelogeninX,Y
CSF1PO12,13
D2S133818
D3S135815
D5S81810
D7S82012
D8S117911,15
D13S3178
D16S5399
D18S5113
D19S43313,14
D21S1130,31.2
FGA22,24
Penta D12
Penta E5,19
TH019
TPOX12
vWA15

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Publications

PubMed=2540861; DOI=10.1182/blood.V73.7.2003.2003
Masaki Nakazawa, Maria-Teresa Mitjavila-Garcia, Najet Debili, Nicole Casadevall, Patrick Mayeux, Philippe Rouyer-Fessard, Anne Dubart-Kupperschmitt, Paul-Henri Romeo, Yves Beuzard, Kenji Kishi, Janine Breton-Gorius, William Vainchenker;
KU 812: a pluripotent human cell line with spontaneous erythroid terminal maturation.
Blood 73:2003-2013(1989)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Cell line collections (Providers) ATCC; CRL-2100
ECACC; 90071803
JCRB; JCRB0104.1
RCB; RCB0496
Cell line databases/resources CLO; CLO_0007126
CLO; CLO_0051000
CLDB; cl3071
cancercelllines; CVCL_0615
CCRID; 1102HUM-NIFDC00110
LINCS_LDP; LCL-1107
Biological sample resources BioSample; SAMN01821694
Encyclopedic resources Wikidata; Q54900695
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number27