ID   Ku812E
AC   CVCL_0615
SY   KU812E; KU-812E; KU 812E
DR   CLO; CLO_0007126
DR   CLO; CLO_0051000
DR   CLDB; cl3071
DR   ATCC; CRL-2100
DR   BioSample; SAMN01821694
DR   cancercelllines; CVCL_0615
DR   CCRID; 1102HUM-NIFDC00110
DR   ECACC; 90071803
DR   JCRB; JCRB0104.1
DR   LINCS_LDP; LCL-1107
DR   RCB; RCB0496
DR   Wikidata; Q54900695
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=2540861;
CC   Population: Japanese.
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Arg (c.395A>G); ClinVar=VCV000376625; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: Basophil progenitor cell; CL=CL_0000613.
ST   Source(s): ATCC=CRL-2100; CCRID=1102HUM-NIFDC00110; JCRB=JCRB0104.1; RCB=RCB0496
ST   Amelogenin: X,Y
ST   CSF1PO: 12,13
ST   D13S317: 8
ST   D16S539: 9
ST   D18S51: 13
ST   D19S433: 13,14
ST   D21S11: 30,31.2
ST   D2S1338: 18
ST   D3S1358: 15
ST   D5S818: 10
ST   D7S820: 12
ST   D8S1179: 11,15
ST   FGA: 22,24
ST   Penta D: 12
ST   Penta E: 5,19
ST   TH01: 9
ST   TPOX: 12
ST   vWA: 15
DI   NCIt; C3174; Chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0379 ! Ku812
SX   Male
AG   38Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 27
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler, Hans Gunther
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=2540861; DOI=10.1182/blood.V73.7.2003.2003;
RA   Nakazawa, Masaki
RA   Mitjavila-Garcia, Maria-Teresa
RA   Debili, Najet
RA   Casadevall, Nicole
RA   Mayeux, Patrick
RA   Rouyer-Fessard, Philippe
RA   Dubart-Kupperschmitt, Anne
RA   Romeo, Paul-Henri
RA   Beuzard, Yves
RA   Kishi, Kenji
RA   Breton-Gorius, Janine
RA   Vainchenker, William
RT   "KU 812: a pluripotent human cell line with spontaneous erythroid
RT   terminal maturation.";
RL   Blood 73:2003-2013(1989).
//