Cellosaurus cell line UW228-3 (CVCL

Cellosaurus UW228-3 (CVCL_0573)

Cross-references
Cell line name	UW228-3
Accession	CVCL_0573
Resource Identification Initiative	To cite this cell line use: UW228-3 (RRID:CVCL_0573)
Comments	Doubling time: 29.0 +- 2.0 hours (PubMed=8866661). Derived from site: In situ; Brain, posterior fossa; UBERON=UBERON_0008788.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr155Asn (c.464C>A); ClinVar=VCV000406564; Zygosity=Unspecified (from parent cell line).
Disease	Medulloblastoma, SHH-activated, TP53-mutant (NCIt: C129442) Medulloblastoma (ORDO: Orphanet_616)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_8585 (UW228)
Sex of cell	Female
Age at sampling	9Y
Category	Cancer cell line
Publications	PubMed=8866661 Guven Evren Keles, Mitchel Stuart Berger, Jayashree Srinivasan, Douglas D. Kolstoe, Michael S. Bobola, John R. Silber; Establishment and characterization of four human medulloblastoma-derived cell lines. Oncol. Res. 7:493-503(1995) PubMed=8674085; DOI=10.1007/BF00819500 Jayashree Srinivasan, Mitchel Stuart Berger, John R. Silber; p53 expression in four human medulloblastoma-derived cell lines. Childs Nerv. Syst. 12:76-80(1996) PubMed=15814657; DOI=10.1158/1078-0432.CCR-04-2045 Michael S. Bobola, John R. Silber, Richard G. Ellenbogen, J. Russell Geyer, A. Blank, Ryan David Goff; O6-methylguanine-DNA methyltransferase, O6-benzylguanine, and resistance to clinical alkylators in pediatric primary brain tumor cell lines. Clin. Cancer Res. 11:2747-2755(2005)
Cell line databases/resources	MCCL; MCC:0000478 cancercelllines; CVCL_0573
Anatomy/cell type resources	BTO; BTO_0004332
Encyclopedic resources	Wikidata; Q54992375
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	22