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Cellosaurus SK-N-MC (CVCL_0530)

[Text version]
Cell line name SK-N-MC
Synonyms SKNMC; SK-NM-C; SK-NMC
Accession CVCL_0530
Resource Identification Initiative To cite this cell line use: SK-N-MC (RRID:CVCL_0530)
Comments Problematic cell line: Misclassified. Originally thought to be a neuroblastoma cell line but shown to be from an Askin tumor (PubMed=20143388).
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: ENCODE project common cell types; tier 3.
Part of: Ewing Sarcoma Cell Line Atlas (ESCLA).
From: Memorial Sloan Kettering Cancer Center; New York; USA.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00267.
Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK 776.
Population: Caucasian.
Doubling time: 32 hours (PubMed=4748425); 23 hours (PubMed=24312454); ~32 hours (CLS=300340); ~48 hours (DSMZ=ACC-203).
Omics: Genomics; ChIP-seq; FLI1.
Omics: Genomics; ChIP-seq; H3K27ac.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Genomics; Whole genome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Orbital region; UBERON=UBERON_0004088.
Sequence variations
HLA typing Source: PubMed=26589293
Class I
HLA-AA*01:01,25:01
HLA-BB*08:01,08:01
HLA-CC*07:01,07:01
Class II
HLA-DQDQA1*05:02,05:02
DQB1*02:02,05:01
HLA-DRDRB1*03:38,12:27
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.84
Native American0
East Asian, North0.61
East Asian, South0
South Asian0.27
European, North67.85
European, South29.43
Disease Askin tumor (NCIt: C7542)
Peripheral primitive neuroectodermal tumor (ORDO: Orphanet_370348)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_1398 (SK-N-MC-IXC)CVCL_WY49 (SKF5)CVCL_WY50 (SKF6)
Sex of cell Female
Age at sampling 12Y
Category Cancer cell line
STR profile Source(s): ATCC=HTB-10; CCRID; CLS=300340; COG; DSMZ=ACC-203; KCLB=30010; PubMed=19787792; PubMed=24312454; PubMed=25010205; PubMed=30879952

Markers:
AmelogeninX
CSF1PO10
D2S133817,21
D3S135815 (ATCC=HTB-10; CLS=300340; KCLB=30010; PubMed=19787792; PubMed=30879952)
15,16 (CCRID; DSMZ=ACC-203; PubMed=24312454; PubMed=25010205)
D5S81811
D7S8208
D8S117910
D13S31711
D16S53912
D18S5113,14 (ATCC=HTB-10; CCRID; CLS=300340; DSMZ=ACC-203; PubMed=24312454; PubMed=25010205)
14 (PubMed=19787792)
D19S43313,15.2 (ATCC=HTB-10; CCRID; PubMed=19787792; PubMed=24312454; PubMed=25010205)
13,16 (DSMZ=ACC-203)
D21S1130,31.2 (ATCC=HTB-10; CLS=300340; COG; DSMZ=ACC-203; PubMed=19787792; PubMed=24312454; PubMed=25010205)
30,31.2,32.2 (CCRID)
FGA21,25
Penta D8,9,13 (DSMZ=ACC-203)
9,13 (ATCC=HTB-10; CLS=300340)
Penta E16,18
SE3316
TH019.3
TPOX9,11 (ATCC=HTB-10; CCRID; CLS=300340; COG; DSMZ=ACC-203; KCLB=30010; PubMed=24312454; PubMed=25010205; PubMed=30879952)
11 (PubMed=19787792)
vWA17,18

Run an STR similarity search on this cell line
Web pages Info; ENCODE; -; http://genome.ucsc.edu/ENCODE/protocols/cell/human/SK-N-MC_protocol.pdf
Info; ESCLA; -; https://hgserver1.amc.nl/cgi-bin/r2/main.cgi?option=about_dscope
Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/s/cell-lines-detail-97.html
Provider; MSKCC; -; https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-n-mc-human-neuroblastoma-cell-line
Publications

PubMed=4748425
June Lee Biedler, Lawrence Helson, Barbara A. Spengler;
Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture.
Cancer Res. 33:2643-2652(1973)

DOI=10.1007/978-1-4757-1647-4_13
June Lee Biedler;
Chromosome abnormalities in human tumor cells in culture.
(In book chapter) Human tumor cells in vitro; Fogh, Jorgen (eds.); pp.359-394; Springer; New York; USA (1975)

PubMed=62055; DOI=10.1093/jnci/57.3.683
June Lee Biedler, Barbara A. Spengler;
A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture.
J. Natl. Cancer Inst. 57:683-695(1976)

PubMed=327080; DOI=10.1093/jnci/59.1.221
Jorgen Fogh, Jens M. Fogh, Thomas Orfeo;
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=29704
June Lee Biedler, Suzanne Roffler-Tarlov, Melitta Schachner, Lewis S. Freedman;
Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones.
Cancer Res. 38:3751-3757(1978)

PubMed=7459858
Monique Rousset, Alain Zweibaum, Jorgen Fogh;
Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.
Cancer Res. 41:1165-1170(1981)

PubMed=7037175
Charles Patrick Reynolds, Debra A. Reynolds, Eugene Philip Frenkel, R. Graham Smith;
Selective toxicity of 6-hydroxydopamine and ascorbate for human neuroblastoma in vitro: a model for clearing marrow prior to autologous transplant.
Cancer Res. 42:1331-1336(1982)

DOI=10.1016/B978-0-12-008304-6.50015-4
June Lee Biedler, Marian B. Meyers, Barbara A. Spengler;
Homogeneously staining regions and double minute chromosomes, prevalent cytogenetic abnormalities of human neuroblastoma cells.
(In book chapter) Advances in cellular neurobiology, Vol. 4; Fedoroff, Sergey & Hertz, Leif (eds.); pp.267-307; Academic Press; New York; USA (1983)

PubMed=6582512; DOI=10.1073/pnas.81.2.568; PMCID=PMC344720
Michael Jules Mattes, Carlos Cordon-Cardo, John L. Lewis Jr., Lloyd John Old, Kenneth Oliver Lloyd;
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

PubMed=2987426; DOI=10.1007/BF00165170
Lawrence Helson, Christiane Helson;
Human neuroblastoma cells and 13-cis-retinoic acid.
J. Neurooncol. 3:39-41(1985)

PubMed=3518877; DOI=10.3109/07357908609038260
Jorgen Fogh;
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2784858; DOI=10.1073/pnas.86.8.2804; PMCID=PMC287007
Alexander Knuth, Thomas Wolfel, Eva Klehmann-Hieb, Thierry Boon, Karl-Hermann Meyer zum Buschenfelde;
Cytolytic T-cell clones against an autologous human melanoma: specificity study and definition of three antigens by immunoselection.
Proc. Natl. Acad. Sci. U.S.A. 86:2804-2808(1989)

PubMed=8378080
Heinrich Kovar, Andreas Auinger, Gunhild Jug, Dave N.T. Aryee, Andreas Zoubek, Mechthild Salzer-Kuntschik, Helmut Gadner;
Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours.
Oncogene 8:2683-2690(1993)

DOI=10.1016/B978-0-12-333530-2.50006-X
Mark A. Israel, Carol Jeanne Thiele;
Tumor cell lines of the peripheral nervous system.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.43-78; Academic Press; New York; USA (1994)

PubMed=8040301; DOI=10.1172/JCI117360; PMCID=PMC295111
Marco Giovannini, Jaclyn A. Biegel, Massimo Serra, Jian-Ying Wang, Ya-Lin H. Wei, Lynn M. Nycum, Beverly S. Emanuel, Glen A. Evans;
EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant translocations.
J. Clin. Invest. 94:489-496(1994)

PubMed=7591257; DOI=10.1002/ijc.2910630407
Kohmei Ida, Shigetoshi Kobayashi, Tomohiko Taki, Ryoji Hanada, Fumio Bessho, Shunji Yamamori, Toru Sugimoto, Misao Ohki, Yasuhide Hayashi;
EWS-FLI-1 and EWS-ERG chimeric mRNAs in Ewing's sarcoma and primitive neuroectodermal tumor.
Int. J. Cancer 63:500-504(1995)

PubMed=8570170
David H.J. van Weering, Jan Paul Medema, Andre A.F.L. van Puijenbroek, Boudewijn M.T. Burgering, Pieter D. Baas, Johannes Lukas Bos;
Ret receptor tyrosine kinase activates extracellular signal-regulated kinase 2 in SK-N-MC cells.
Oncogene 11:2207-2214(1995)

PubMed=8617485; DOI=10.1016/S0046-8177(96)90115-X
Katia Scotlandi, Massimo Serra, Maria Cristina Manara, Stefania Benini, Manuela Sarti, Daniela Maurici, Pier-Luigi Lollini, Piero Picci, Francesco Bertoni, Nicola Baldini;
Immunostaining of the p30/32MIC2 antigen and molecular detection of EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumor.
Hum. Pathol. 27:408-416(1996)

PubMed=8665486; DOI=10.1016/0304-3835(96)04250-4
Mitchell B. Diccianni, Lan S. Chau, Ayse Batova, Thai Q. Vu, Alice Lin-Tsing Yu;
The p16 and p18 tumor suppressor genes in neuroblastoma: implications for drug resistance.
Cancer Lett. 104:183-192(1996)

PubMed=9121763; DOI=10.1038/sj.onc.1200911
Andre A.F.L. van Puijenbroek, David H.J. van Weering, Christina E. van den Brink, Johannes Lukas Bos, Paul T. van der Saag, Siegfried Wolfgang de Laat, Jeroen den Hertog;
Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation.
Oncogene 14:1147-1157(1997)

PubMed=11668190; DOI=10.1177/002215540104901105
Hilmar Quentmeier, Mary Osborn, Julia Reinhardt, Margarete Zaborski, Hans Gunther Drexler;
Immunocytochemical analysis of cell lines derived from solid tumors.
J. Histochem. Cytochem. 49:1369-1378(2001)

PubMed=15390183; DOI=10.1002/gcc.20096
Sigrun Gebauer, Alice Lin-Tsing Yu, Motoko Omura-Minamisawa, Ayse Batova, Mitchell B. Diccianni;
Expression profiles and clinical relationships of ID2, CDKN1B, and CDKN2A in primary neuroblastoma.
Genes Chromosomes Cancer 41:297-308(2004)

PubMed=18160777; DOI=10.1159/000109614
Suvi Savola, Filippo Nardi, Katia Scotlandi, Piero Picci, Sakari Knuutila;
Microdeletions in 9p21.3 induce false negative results in CDKN2A FISH analysis of Ewing sarcoma.
Cytogenet. Genome Res. 119:21-26(2007)

PubMed=19787792; DOI=10.1002/gcc.20717
Laura Ottaviano, Karl-Ludwig Schaefer, Melanie Gajewski, Wolfgang Huckenbeck, Stefan E. Baldus, Uwe Rogel, Carlos Mackintosh, Enrique de Alava, Ola Myklebost, Stine Henrichson Kresse, Leonardo Andres Meza-Zepeda ...Show all 18 authors... , Massimo Serra, Anne-Marie Cleton-Jansen, Pancras Cornelis Wilhelmus Hogendoorn, Horst Buerger, Thomas Aigner, Helmut Erich Gabbert, Christopher Poremba; Show fewer authors
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Genes Chromosomes Cancer 49:40-51(2010)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=21822310; DOI=10.1038/onc.2011.317
Carlos Mackintosh, Jose L. Ordonez, Daniel J. Garcia-Dominguez, Vicky Sevillano, Antonio Llombart-Bosch, Karoly Szuhai, Katia Scotlandi, Marco Alberghini, Raf Sciot, Friedl Sinnaeve, Pancras Cornelis Wilhelmus Hogendoorn ...Show all 17 authors... , Piero Picci, Sakari Knuutila, Uta Dirksen, Maria Debiec-Rychter, Karl-Ludwig Schaefer, Enrique de Alava; Show fewer authors
1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma.
Oncogene 31:1287-1298(2012)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23325432; DOI=10.1101/gr.147942.112; PMCID=PMC3589544
Katherine E. Varley, Jason Gertz, Kevin M. Bowling, Stephanie L. Parker, Timothy E. Reddy, Florencia Pauli-Behn, Marie K. Cross, Brian A. Williams, John A. Stamatoyannopoulos, Gregory E. Crawford, Devin Michael Absher ...Show all 13 authors... , Barbara Jane Wold, Richard M. Myers; Show fewer authors
Dynamic DNA methylation across diverse human cell lines and tissues.
Genome Res. 23:555-567(2013)

PubMed=24312454; DOI=10.1371/journal.pone.0080060; PMCID=PMC3846563
William A. May, Rita S. Grigoryan, Nino Keshelava, Daniel J. Cabral, Laura L. Christensen, Jasmine Jenabi, Ling-Yun Ji, Timothy J. Triche, Elizabeth R. Lawlor, Charles Patrick Reynolds;
Characterization and drug resistance patterns of Ewing's sarcoma family tumor cell lines.
PLoS ONE 8:e80060.1-e80060.10(2013)

PubMed=25010205; DOI=10.1371/journal.pgen.1004475; PMCID=PMC4091782
Andrew S. Brohl, David A. Solomon, Wendy Chang, Jian-Jun Wang, Young Song, Sivasish Sindiri, Rajesh Patidar, Laura Hurd, Li Chen, Jack F. Shern, Hong-Ling Liao ...Show all 26 authors... , Xin-Yu Wen, Julia Gerard, Jung-Sik Kim, Jose Antonio Lopez Guerrero, Isidro Machado, Daniel H. Wai, Piero Picci, Timothy J. Triche, Andrew E. Horvai, Markku Martti Miettinen, Jun S. Wei, Daniel Catchpoole, Antonio Llombart-Bosch, Todd A. Waldman, Javed Khan; Show fewer authors
The genomic landscape of the Ewing sarcoma family of tumors reveals recurrent STAG2 mutation.
PLoS Genet. 10:e1004475.1-e1004475.13(2014)

PubMed=25223734; DOI=10.1158/2159-8290.CD-14-0622; PMCID=PMC4264969
Franck Tirode, Didier Surdez, Xiao-Tu Ma, Matthew Parker, Marie-Cecile Le Deley, Armita Bahrami, Zhao-Jie Zhang, Eve Lapouble, Sandrine Grossetete-Lalami, Michael Rusch, Stephanie Reynaud ...Show all 35 authors... , Thomas Rio-Frio, Erin Hedlund, Gang Wu, Xiang Chen, Gaelle Pierron, Odile Oberlin, Sakina Zaidi, Gordon Lemmon, Pankaj Gupta, Bhavin Vadodaria, John Easton, Marta Gut, Li Ding, Elaine R. Mardis, Richard K. Wilson, Sheila Shurtleff, Valerie Laurence, Jean Michon, Perrine Marec-Berard, Ivo G. Gut, James R. Downing, Michael Anthony Dyer, Jing-Hui Zhang, Olivier Delattre; Show fewer authors
International Cancer Genome Consortium
St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project
Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations.
Cancer Discov. 4:1342-1353(2014)

PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074; PMCID=PMC4636476
Beverly A. Teicher, Eric C. Polley, Mark W. Kunkel, David Evans, Thomas E. Silvers, Rene M. Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Michael Selby, John Connelly ...Show all 14 authors... , Erik Harris, Anne Monks, Joel Morris; Show fewer authors
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Mol. Cancer Ther. 14:2452-2462(2015)

PubMed=26428435; DOI=10.1016/j.ejca.2015.08.020
Laurens G.L. Sand, Katia Scotlandi, Dagmar Berghuis, B. Ewa Snaar-Jagalska, Piero Picci, Thomas Schmidt, Karoly Szuhai, Pancras Cornelis Wilhelmus Hogendoorn;
CXCL14, CXCR7 expression and CXCR4 splice variant ratio associate with survival and metastases in Ewing sarcoma patients.
Eur. J. Cancer 51:2624-2633(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=30879952; DOI=10.1016/j.ymthe.2019.02.014; PMCID=PMC6520468
Sareetha Kailayangiri, Bianca Altvater, Stefanie Lesch, Sebastian T. Balbach, Claudia Gottlich, Johanna Kuhnemundt, Jan-Henrik Mikesch, Sonja Schelhaas, Silke Jamitzky, Jutta Meltzer, Nicole Farwick ...Show all 20 authors... , Lea Greune, Maike Fluegge, Kornelius Kerl, Holger N. Lode, Nikolai Siebert, Ingo Muller, Heike Walles, Wolfgang Hartmann, Claudia Rossig; Show fewer authors
EZH2 inhibition in Ewing sarcoma upregulates GD2 expression for targeting with gene-modified T cells.
Mol. Ther. 27:933-946(2019)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254
David Paul Nusinow, John Szpyt, Mahmoud Ghandi, Christopher M. Rose, E. Robert McDonald 3rd, Marian Kalocsay, Judit Jane-Valbuena, Ellen T. Gelfand, Devin K. Schweppe, Mark P. Jedrychowski, Javad Golji ...Show all 20 authors... , Dale A. Porter, Tomas Rejtar, Y. Karen Wang, Gregory V. Kryukov, Frank Stegmeier, Brian K. Erickson, Levi Alexander Garraway, William Raj Sellers, Steven P. Gygi; Show fewer authors
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)

DOI=10.5282/edoc.27750
Martin Franz Orth;
Systematic multi-omics profiling of Ewing sarcoma cell lines.
Thesis PhD (2021); Ludwig Maximilians University of Munich; Munich; Germany

PubMed=36476851; DOI=10.1016/j.celrep.2022.111761; PMCID=PMC10333306
Martin Franz Orth, Didier Surdez, Tobias Faehling, Anna C. Ehlers, Aruna Marchetto, Sandrine Grossetete-Lalami, Richard Volckmann, Danny A. Zwijnenburg, Julia Sophie Gerke, Sakina Zaidi, Javier Alonso ...Show all 25 authors... , Ana Sastre, Sylvain Baulande, Martin Sill, Florencia Cidre-Aranaz, Shunya Ohmura, Thomas Kirchner, Stefanie M. Hauck, Eva Reischl, Melissa Gymrek, Stefan Michael Pfister, Konstantin Strauch, Jan Koster, Olivier Delattre, Thomas Georg Philipp Grunewald; Show fewer authors
Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation.
Cell Rep. 41:111761.1-111761.28(2022)

Cross-references
Cell line collections (Providers) ATCC; HTB-10
CancerTools; 161936
CLS; 300340
DSMZ; ACC-203
ECACC; 90022302
IZSLER; BS TCL 93
KCB; KCB 2012033YJ
KCLB; 30010
NCBI_Iran; C535
Cell line databases/resources CLO; CLO_0009058
MCCL; MCC:0000429
CLDB; cl4338
CLDB; cl4339
CLDB; cl4340
CLDB; cl4341
CLDB; cl4342
CLDB; cl4343
cancercelllines; CVCL_0530
CCRID; 1101HUM-PUMC000263
CCRID; 3101HUMTCHu50
Cell_Model_Passport; SIDM00634
DepMap; ACH-000039
DSMZCellDive; ACC-203
IGRhCellID; SKNMC%20GEO
Lonza; 82
TOKU-E; 3148
Anatomy/cell type resources BTO; BTO_0002914
Biological sample resources 4DN; 4DNSRW6BI5JA
BioSample; SAMN01821666
BioSample; SAMN03151999
BioSample; SAMN10987896
ENCODE; ENCBS203EZT
ENCODE; ENCBS255ORK
ENCODE; ENCBS273LIC
ENCODE; ENCBS357PJT
ENCODE; ENCBS366AET
ENCODE; ENCBS387QLW
ENCODE; ENCBS400ENC
ENCODE; ENCBS423QPB
ENCODE; ENCBS426ENC
ENCODE; ENCBS556HGY
ENCODE; ENCBS734TWP
CRISP screens repositories BioGRID_ORCS_Cell_line; 462
Chemistry resources ChEMBL-Cells; CHEMBL3307551
ChEMBL-Targets; CHEMBL614163
PharmacoDB; SKNMC_1408_2019
PubChem_Cell_line; CVCL_0530
Encyclopedic resources Wikidata; Q54954478
Experimental variables resources EFO; EFO_0002860
Gene expression databases ArrayExpress; E-MTAB-2770
FANTOM5_SSTAR; 10728-110A8
GEO; GSM393038
GEO; GSM510009
GEO; GSM824868
GEO; GSM824869
GEO; GSM887596
GEO; GSM888679
GEO; GSM945247
GEO; GSM945264
GEO; GSM1022638
GEO; GSM1676318
GEO; GSM1701651
GEO; GSM5359700
GEO; GSM5359701
GEO; GSM5359702
GEO; GSM5359703
GEO; GSM5359704
GEO; GSM5359705
GEO; GSM5362882
GEO; GSM5362883
GEO; GSM5362890
GEO; GSM5362891
GEO; GSM5362898
GEO; GSM5362899
GEO; GSM5364006
GEO; GSM5364007
GEO; GSM5364008
GEO; GSM5364009
GEO; GSM5364010
Polymorphism and mutation databases Cosmic; 753613
Cosmic; 897448
Cosmic; 922655
Cosmic; 1078367
Cosmic; 1078391
Cosmic; 1082511
Cosmic; 1084314
Cosmic; 2228233
Cosmic; 2250468
Cosmic; 2301579
IARC_TP53; 23586
LiGeA; CCLE_596
Progenetix; CVCL_0530
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number46