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Cellosaurus Rat1 (CVCL_0492)

[Text version]

Cell line name Rat1
Synonyms Rat-1; RAT-1; Rat 1
Accession CVCL_0492
Resource Identification Initiative To cite this cell line use: Rat1 (RRID:CVCL_0492)
Comments Doubling time: 16-20 hours (PubMed=8668197).
Derived from sampling site: Whole embryo. Cell type=Fibroblast.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344.
Hierarchy Parent: CVCL_8352 (F2408)
Children:
CVCL_4086 (208F )CVCL_0300 (HIRcB )CVCL_VU46 (R70-15 )
CVCL_VU49 (R80-1 )CVCL_VU50 (R80-6 )CVCL_U152 (Rat-1/BB16 )
CVCL_U153 (Rat-1/tsLA29 )CVCL_4695 (Rat1-R12 )CVCL_0512 (Rat1A )
CVCL_0513 (Rat2 )CVCL_G296 (RatB1a )CVCL_T955 (TGR-1 )
Sex of cell Sex unspecified
Age at sampling Embryo
Category Spontaneously immortalized cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/r/cell-lines-detail-373.html
Publications

PubMed=6307528; DOI=10.1016/0092-8674(83)90036-3
Kaplan P.L., Ozanne B.
Cellular responsiveness to growth factors correlates with a cell's ability to express the transformed phenotype.
Cell 33:931-938(1983)

PubMed=3677083
Reynolds V.L., DiPietro M., Lebovitz R.M., Lieberman M.W.
Inherent tumorigenic and metastatic properties of rat-1 and rat-2 cells.
Cancer Res. 47:6384-6387(1987)

PubMed=8668197; DOI=10.1128/mcb.16.7.3799
Yang S.-H., Nussenzweig A., Li L., Kim D., Ouyang H.-H., Burgman P., Li G.C.
Modulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits.
Mol. Cell. Biol. 16:3799-3806(1996)

PubMed=9724713; DOI=10.1073/pnas.95.18.10390
Ghoshal K., Li Z., Jacob S.T.
Overexpression of the large subunit of the protein Ku suppresses metallothionein-I induction by heavy metals.
Proc. Natl. Acad. Sci. U.S.A. 95:10390-10395(1998)

Cross-references
Cell line collections RCB; RCB1830
Cell line databases/resources CLO; CLO_0050238
MCCL; MCC:0000389
Anatomy/cell type resources BTO; BTO:0003293
Chemistry resources ChEMBL-Cells; CHEMBL3307665
ChEMBL-Targets; CHEMBL614630
Encyclopedic resources Wikidata; Q54949236
Entry history
Entry creation04-Apr-2012
Last entry update17-Mar-2022
Version number14