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Cellosaurus R70-15 (CVCL_VU46)

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Cell line name R70-15
Accession CVCL_VU46
Resource Identification Initiative To cite this cell line use: R70-15 (RRID:CVCL_VU46)
Comments Doubling time: 16-20 hours (PubMed=8668197).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:4055; XRCC6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Hierarchy Parent: CVCL_0492 (Rat1)
Children:
CVCL_VU47 (R7080-20)CVCL_VU48 (R7080-6)
Sex of cell Male
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=8668197; DOI=10.1128/mcb.16.7.3799; PMCID=PMC231376
Shao-Hua Yang, Andre Nussenzweig, Li-Geng Li, Dooha Kim, Hong-Hai Ouyang, Paul Burgman, Gloria C. Li;
Modulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits.
Mol. Cell. Biol. 16:3799-3806(1996)

PubMed=9724713; DOI=10.1073/pnas.95.18.10390; PMCID=PMC27904
Kalpana Ghoshal, Zhi-Ling Li, Samson T. Jacob;
Overexpression of the large subunit of the protein Ku suppresses metallothionein-I induction by heavy metals.
Proc. Natl. Acad. Sci. U.S.A. 95:10390-10395(1998)

Cross-references
Encyclopedic resources Wikidata; Q98128784
Entry history
Entry creation24-May-2019
Last entry update10-Apr-2025
Version number8