ID   Rat1
AC   CVCL_0492
SY   Rat-1; RAT-1; Rat 1
DR   BTO; BTO:0003293
DR   CLO; CLO_0050238
DR   MCCL; MCC:0000389
DR   ChEMBL-Cells; CHEMBL3307665
DR   ChEMBL-Targets; CHEMBL614630
DR   PubChem_Cell_line; CVCL_0492
DR   RCB; RCB1830
DR   Wikidata; Q54949236
RX   PubMed=3677083;
RX   PubMed=6307528;
RX   PubMed=8668197;
RX   PubMed=9724713;
CC   Doubling time: 16-20 hours (PubMed=8668197).
CC   Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: Fischer 344.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_8352 ! F2408
SX   Sex unspecified
AG   Embryo
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 17
RX   PubMed=3677083;
RA   Reynolds V.L., DiPietro M., Lebovitz R.M., Lieberman M.W.;
RT   "Inherent tumorigenic and metastatic properties of rat-1 and rat-2
RT   cells.";
RL   Cancer Res. 47:6384-6387(1987).
RX   PubMed=6307528; DOI=10.1016/0092-8674(83)90036-3;
RA   Kaplan P.L., Ozanne B.;
RT   "Cellular responsiveness to growth factors correlates with a cell's
RT   ability to express the transformed phenotype.";
RL   Cell 33:931-938(1983).
RX   PubMed=8668197; DOI=10.1128/mcb.16.7.3799;
RA   Yang S.-H., Nussenzweig A., Li L.-G., Kim D., Ouyang H.-H., Burgman P.,
RA   Li G.C.;
RT   "Modulation of thermal induction of hsp70 expression by Ku autoantigen
RT   or its individual subunits.";
RL   Mol. Cell. Biol. 16:3799-3806(1996).
RX   PubMed=9724713; DOI=10.1073/pnas.95.18.10390;
RA   Ghoshal K., Li Z.-L., Jacob S.T.;
RT   "Overexpression of the large subunit of the protein Ku suppresses
RT   metallothionein-I induction by heavy metals.";
RL   Proc. Natl. Acad. Sci. U.S.A. 95:10390-10395(1998).