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Cellosaurus CTLL-2 (CVCL_0227)

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Cell line name CTLL-2
Synonyms CTLL 2; CTLL2; CTLL(2)
Accession CVCL_0227
Resource Identification Initiative To cite this cell line use: CTLL-2 (RRID:CVCL_0227)
Comments Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Characteristics: IL2 dependent.
Doubling time: 24 hours (PubMed=145543).
Cell type: T-cell; CL=CL_0000084.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_KS71 (CellSensor irf1-bla CTLL-2)CVCL_6829 (CT.EV)CVCL_D100 (CTL44)
CVCL_YU23 (CTLL-2 NF-kappaB)CVCL_9786 (CTLL-20)
Category Transformed cell line
STR profile Source(s): PubMed=31220119

Markers:
Mouse STR 1-117
Mouse STR 1-219,20
Mouse STR 2-115,16
Mouse STR 3-214
Mouse STR 4-220.3
Mouse STR 5-517,18
Mouse STR 6-418,19
Mouse STR 6-717,20
Mouse STR 7-126.2
Mouse STR 8-116
Mouse STR 11-216
Mouse STR 12-117
Mouse STR 13-116
Mouse STR 15-322.3,23.3
Mouse STR 17-214,15
Mouse STR 18-316
Mouse STR 19-213,14
Mouse STR X-128,29

Run an STR similarity search on this cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=CTLL-2
Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-67.html
Publications

PubMed=145543; DOI=10.1038/268154a0
Steven Gillis, Kendall Arthur Smith;
Long term culture of tumour-specific cytotoxic T cells.
Nature 268:154-156(1977)

PubMed=9619491; DOI=10.1046/j.1440-1711.1998.00733.x
Lyanne Weston, Andrew Geczy, Caroline Farrell;
A convenient and reliable IL-2 bioassay using frozen CTLL-2 to improve the detection of helper T lymphocyte precursors.
Immunol. Cell Biol. 76:190-192(1998)

PubMed=9744750; DOI=10.1016/S0022-1759(98)00065-9
Marie Winandy, Philippe Lewalle, Veronique Deneys, Augustin Ferrant, Marc De Bruyere;
Improved IL-2 detection for determination of helper T lymphocyte precursor frequency in limiting dilution assay.
J. Immunol. Methods 215:81-94(1998)

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308
Jamie L. Almeida, Aleksandra Dakic, Karin Kindig, Maikan Kone, Deborah Lee Dormady Letham, Scott Langdon, Ruth Peat, Jayamalini Holding-Pillai, Erin M. Hall, Mark Ladd, Megan D. Shaffer ...Show all 23 authors... , Heath Berg, Jin-Liang Li, Georges Wigger, Steve Lund, Carolyn R. Steffen, Barbara B. Fransway, Bob Geraghty, Manuela Natoli, Beth A. Bauer, Susanne M. Gollin, Dale W. Lewis, Yvonne A. Reid; Show fewer authors
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:e0218412.1-e0218412.24(2019)

Cross-references
Cell line collections (Providers) ATCC; TIB-214
BCRC; 60376
BCRJ; 0281 - Discontinued
CLS; 400482
DSMZ; ACC-27 - Discontinued
ECACC; 93042610
ICLC; AL00003
NCBI_Iran; C538
RCB; RCB0637
Cell line databases/resources CLO; CLO_0002636
CLO; CLO_0050181
MCCL; MCC:0000115
CLDB; cl925
CLDB; cl4995
CCRID; 1102MOU-NIFDC00051
CCRID; 3101MOUGNM4
DSMZCellDive; ACC-27
Lonza; 1012
Anatomy/cell type resources BTO; BTO_0001482
Biological sample resources BioSample; SAMN11397659
Encyclopedic resources Wikidata; Q54814742
Experimental variables resources EFO; EFO_0002821
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number29