ID   CTLL-2
AC   CVCL_0227
SY   CTLL 2; CTLL2; CTLL(2)
DR   BTO; BTO_0001482
DR   CLO; CLO_0002636
DR   CLO; CLO_0050181
DR   EFO; EFO_0002821
DR   MCCL; MCC:0000115
DR   CLDB; cl925
DR   CLDB; cl4995
DR   ATCC; TIB-214
DR   BCRC; 60376
DR   BCRJ; 0281
DR   BioSample; SAMN11397659
DR   CCRID; 1102MOU-NIFDC00051
DR   CCRID; 3101MOUGNM4
DR   CLS; 400482
DR   DSMZ; ACC-27
DR   DSMZCellDive; ACC-27
DR   ECACC; 93042610
DR   ICLC; AL00003
DR   Lonza; 1012
DR   NCBI_Iran; C538
DR   RCB; RCB0637
DR   Wikidata; Q54814742
RX   PubMed=145543;
RX   PubMed=9619491;
RX   PubMed=9744750;
RX   PubMed=31220119;
WW   Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=CTLL-2
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-67.html
CC   Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
CC   Characteristics: IL2 dependent.
CC   Doubling time: 24 hours (PubMed=145543).
CC   Discontinued: BCRJ; 0281; probable.
CC   Discontinued: DSMZ; ACC-27; true.
CC   Cell type: T-cell; CL=CL_0000084.
CC   Breed/subspecies: C57BL/6.
ST   Source(s): PubMed=31220119
ST   Mouse STR 1-1: 17
ST   Mouse STR 1-2: 19,20
ST   Mouse STR 2-1: 15,16
ST   Mouse STR 3-2: 14
ST   Mouse STR 4-2: 20.3
ST   Mouse STR 5-5: 17,18
ST   Mouse STR 6-4: 18,19
ST   Mouse STR 6-7: 17,20
ST   Mouse STR 7-1: 26.2
ST   Mouse STR 8-1: 16
ST   Mouse STR 11-2: 16
ST   Mouse STR 12-1: 17
ST   Mouse STR 13-1: 16
ST   Mouse STR 15-3: 22.3,23.3
ST   Mouse STR 17-2: 14,15
ST   Mouse STR 18-3: 16
ST   Mouse STR 19-2: 13,14
ST   Mouse STR X-1: 28,29
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 29
CH   CVCL_KS71 ! CellSensor irf1-bla CTLL-2
CH   CVCL_6829 ! CT.EV
CH   CVCL_D100 ! CTL44
CH   CVCL_YU23 ! CTLL-2 NF-kappaB
CH   CVCL_9786 ! CTLL-20
//
RX   PubMed=145543; DOI=10.1038/268154a0;
RA   Gillis, Steven
RA   Smith, Kendall Arthur
RT   "Long term culture of tumour-specific cytotoxic T cells.";
RL   Nature 268:154-156(1977).
//
RX   PubMed=9744750; DOI=10.1016/S0022-1759(98)00065-9;
RA   Winandy, Marie
RA   Lewalle, Philippe
RA   Deneys, Veronique
RA   Ferrant, Augustin
RA   De Bruyere, Marc
RT   "Improved IL-2 detection for determination of helper T lymphocyte
RT   precursor frequency in limiting dilution assay.";
RL   J. Immunol. Methods 215:81-94(1998).
//
RX   PubMed=9619491; DOI=10.1046/j.1440-1711.1998.00733.x;
RA   Weston, Lyanne
RA   Geczy, Andrew
RA   Farrell, Caroline
RT   "A convenient and reliable IL-2 bioassay using frozen CTLL-2 to
RT   improve the detection of helper T lymphocyte precursors.";
RL   Immunol. Cell Biol. 76:190-192(1998).
//
RX   PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308;
RA   Almeida, Jamie L.
RA   Dakic, Aleksandra
RA   Kindig, Karin
RA   Kone, Maikan
RA   Letham, Deborah Lee Dormady
RA   Langdon, Scott
RA   Peat, Ruth
RA   Holding-Pillai, Jayamalini
RA   Hall, Erin M.
RA   Ladd, Mark
RA   Shaffer, Megan D.
RA   Berg, Heath
RA   Li, Jin-Liang
RA   Wigger, Georges
RA   Lund, Steve
RA   Steffen, Carolyn R.
RA   Fransway, Barbara B.
RA   Geraghty, Bob
RA   Natoli, Manuela
RA   Bauer, Beth A.
RA   Gollin, Susanne M.
RA   Lewis, Dale W.
RA   Reid, Yvonne A.
RT   "Interlaboratory study to validate a STR profiling method for
RT   intraspecies identification of mouse cell lines.";
RL   PLoS ONE 14:e0218412.1-e0218412.24(2019).
//