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Cellosaurus CTLL-2 NF-kappaB (CVCL_YU23)

[Text version]
Cell line name CTLL-2 NF-kappaB
Synonyms CTLL-2_NF-kappaB
Accession CVCL_YU23
Resource Identification Initiative To cite this cell line use: CTLL-2 NF-kappaB (RRID:CVCL_YU23)
Comments Characteristics: Reporter cell line for the measurement of the biological activity of a wide variety of cytokines.
Characteristics: Activated by NF-kappaB through a NF-kappaB response element fused to a secNanoLuc-T2A-mCherry construct.
Transfected with: NanoLuc, a 19 kDa ATP-independent bright luminescent protein derived from Oplophorus gracilirostris.
Transfected with: UniProtKB; X5DSL3; Anaplasma marginale mCherry fluorescent protein.
Cell type: T-cell; CL=CL_0000084.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_0227 (CTLL-2)
Category Transformed cell line
Publications

PubMed=32094407; DOI=10.1038/s41598-020-60182-4
Mock J., Pellegrino C., Neri D.
A universal reporter cell line for bioactivity evaluation of engineered cytokine products.
Sci. Rep. 10:3234-3234(2020)

Cross-references
Encyclopedic resources Wikidata; Q93459998
Entry history
Entry creation12-Mar-2020
Last entry update29-Jun-2023
Version number6