Cellosaurus CTLL-2 NF-kappaB (CVCL_YU23)
| Cell line name | CTLL-2 NF-kappaB |
|---|---|
| Synonyms | CTLL-2_NF-kappaB |
| Accession | CVCL_YU23 |
| Resource Identification Initiative | To cite this cell line use: CTLL-2 NF-kappaB (RRID:CVCL_YU23) |
| Comments | Characteristics: Reporter cell line for the measurement of the biological activity of a wide variety of cytokines. Characteristics: Activated by NF-kappaB through a NF-kappaB response element fused to a secNanoLuc-T2A-mCherry construct. Genetic integration: Method=Transfection/transduction; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)). Genetic integration: Method=Transfection/transduction; Gene=Oplophorus gracilirostris NanoLuc (Note=19 kDa ATP-independent bright luminescent protein derived from O.gracilirostris luciferase). Cell type: T-cell; CL=CL_0000084. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6. |
| Hierarchy | Parent: CVCL_0227 (CTLL-2) |
| Category | Transformed cell line |
| Publications | PubMed=32094407; DOI=10.1038/s41598-020-60182-4; PMCID=PMC7040017 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q93459998 |
| Entry history | |
| Entry creation | 12-Mar-2020 |
| Last entry update | 14-Aug-2025 |
| Version number | 9 |