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Cellosaurus CC-LP-1 (CVCL_0205)

[Text version]

Cell line name CC-LP-1
Synonyms CC-LP-I; CCLP-1; CCLP1
Accession CVCL_0205
Resource Identification Initiative To cite this cell line use: CC-LP-1 (RRID:CVCL_0205)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Doubling time: 180 hours (PubMed=1355757).
Caution: Indicated to derive from a female patient in PubMed=1355757, but has a X,Y amelogenin STR marker.
Derived from sampling site: Liver.
Sequence variations
  • Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly34Val (c.101G>T); ClinVar=VCV000017582; Zygosity=Unspecified (DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Unspecified (DepMap).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): DepMap

Markers:
AmelogeninX,Y
CSF1PO11,13
D3S135815,16
D5S81811,12
D7S82010,11
D8S117911,13
D13S3179,12
D16S5399,13
D18S5113,14
D21S1129,33
FGA22
Penta D12,13
Penta E12
TH019.3
TPOX8,11
vWA15,17

Run an STR similarity search on this cell line
Publications

PubMed=1355757; DOI=10.1002/ijc.2910520217
Shimizu Y., Demetris A.J., Gollin S.M., Storto P.D., Bedford H.M., Altarac S., Iwatsuki S., Herberman R.B., Whiteside T.L.
Two new human cholangiocarcinoma cell lines and their cytogenetics and responses to growth factors, hormones, cytokines or immunologic effector cells.
Int. J. Cancer 52:252-260(1992)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442
Saha S.K., Gordan J.D., Kleinstiver B.P., Vu P., Najem M.S., Yeo J.-C., Shi L., Kato Y., Levin R.S., Webber J.T., Damon L.J., Egan R.K., Greninger P., McDermott U., Garnett M.J., Jenkins R.L., Rieger-Christ K.M., Sullivan T.B., Hezel A.F., Liss A.S., Mizukami Y., Goyal L., Ferrone C.R., Zhu A.X., Joung J.K., Shokat K.M., Benes C.H., Bardeesy N.
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Cancer Discov. 6:727-739(2016)

Cross-references
Cell line databases/resources MCCL; MCC:0000094
Cell_Model_Passport; SIDM01889
DepMap; ACH-001959
TOKU-E; 4041
Anatomy/cell type resources BTO; BTO:0002933
Encyclopedic resources Wikidata; Q54808710
Polymorphism and mutation databases Cosmic; 927189
Entry history
Entry creation04-Apr-2012
Last entry update16-Dec-2021
Version number17