ID CC-LP-1 AC CVCL_0205 SY CC-LP-I; CCLP-1; CCLP1 DR BTO; BTO_0002933 DR MCCL; MCC:0000094 DR cancercelllines; CVCL_0205 DR Cell_Model_Passport; SIDM01889 DR Cosmic; 927189 DR DepMap; ACH-001959 DR TOKU-E; 4041 DR Wikidata; Q54808710 RX CelloPub=CLPUB00275; RX PubMed=1355757; RX PubMed=27231123; RX PubMed=31109923; RX PubMed=35640676; RX PubMed=39026794; CC Part of: Biliary tract cancer cell line atlas. CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Population: Caucasian. CC Doubling time: 180 hours (PubMed=1355757). CC Sequence variation: Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Val (c.101G>T); ClinVar=VCV000017582; Zygosity=Unspecified (DepMap=ACH-001959). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Unspecified (DepMap=ACH-001959). CC Caution: Indicated to derive from a female patient in PubMed=1355757, but has a X,Y amelogenin STR marker. CC Derived from site: In situ; Liver; UBERON=UBERON_0002107. ST Source(s): DepMap=ACH-001959 ST Amelogenin: X,Y ST CSF1PO: 11,13 ST D13S317: 9,12 ST D16S539: 9,13 ST D18S51: 13,14 ST D21S11: 29,33 ST D3S1358: 15,16 ST D5S818: 11,12 ST D7S820: 10,11 ST D8S1179: 11,13 ST FGA: 22 ST Penta D: 12,13 ST Penta E: 12 ST TH01: 9.3 ST TPOX: 8,11 ST vWA: 15,17 DI NCIt; C35417; Intrahepatic cholangiocarcinoma DI ORDO; Orphanet_70567; Cholangiocarcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 48Y CA Cancer cell line DT Created: 04-04-12; Last updated: 19-12-24; Version: 23 // RX PubMed=31109923; DOI=10.1158/2159-8290.CD-19-0182; PMCID=PMC6677584; RA Goyal, Lipika RA Shi, Lei RA Liu, Leah Y. RA Fece de la Cruz, Ferran RA Lennerz, Jochen K. RA Raghavan, Srivatsan RA Leschiner, Ignaty RA Elagina, Liudmila RA Siravegna, Giulia RA Ng, Raymond W.S. RA Vu, Phuong RA Patra, Krushna C. RA Saha, Supriya Kumar RA Uppot, Raul N. RA Arellano, Ronald Steven RA Reyes, Stephanie RA Sagara, Takeshi RA Otsuki, Sachie RA Nadres, Brandon RA Shahzade, Heather A. RA Dey-Guha, Ipsita RA Fetter, Isobel J. RA Baiev, Islam RA Van Seventer, Emily E. RA Murphy, Janet Elaine RA Ferrone, Cristina Rosa RA Tanabe, Kenneth K. RA Deshpande, Vikram RA Harding, James J. RA Yaeger, Rona D. RA Kelley, Robin Kate RA Bardelli, Alberto RA Iafrate, Anthony John RA Hahn, William Chun RA Benes, Cyril Henri RA Ting, David Tsai RA Hirai, Hiroshi RA Getz, Gad RA Juric, Dejan RA Zhu, Andrew Xiu-Xuan RA Corcoran, Ryan Bruce RA Bardeesy, Nabeel M. RT "TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in RT patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma."; RL Cancer Discov. 9:1064-1079(2019). // RX CelloPub=CLPUB00275; RA Zach, Sebastian RA Birgin, Emrullah RA Ruckert, Felix RT "Primary cholangiocellular carcinoma cell lines."; RL J. Stem Cell Res. Transplant. 2:1013-1013(2015). // RX PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155; RA Isidan, Abdulkadir RA Yenigun, Ali RA Soma, Daiki RA Aksu, Eric RA Lopez, Kevin RA Park, Yujin RA Cross-Najafi, Arthur RA Li, Ping RA Kundu, Debjyoti RA House, Michael G. RA Chakraborty, Sanjukta RA Glaser, Shannon RA Kennedy, Lindsey RA Francis, Heather RA Zhang, Wen-Jun RA Alpini, Gianfranco D. RA Ekser, Burcin RT "Development and characterization of human primary cholangiocarcinoma RT cell lines."; RL Am. J. Pathol. 192:1200-1217(2022). // RX PubMed=1355757; DOI=10.1002/ijc.2910520217; RA Shimizu, Yukihiro RA Demetris, Anthony Jacob RA Gollin, Susanne M. RA Storto, Patrick Daniel RA Bedford, H. Melanie RA Altarac, Silvio RA Iwatsuki, Shunzaburo RA Herberman, Ronald Bruce RA Whiteside, Theresa L. RT "Two new human cholangiocarcinoma cell lines and their cytogenetics RT and responses to growth factors, hormones, cytokines or immunologic RT effector cells."; RL Int. J. Cancer 52:252-260(1992). // RX PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737; RA Saha, Supriya Kumar RA Gordan, John D. RA Kleinstiver, Benjamin P. RA Vu, Phuong RA Najem, Mortada S. RA Yeo, Jia-Chi RA Shi, Lei RA Kato, Yasutaka RA Levin, Rebecca S. RA Webber, James T. RA Damon, Leah J. RA Egan, Regina K. RA Greninger, Patricia RA McDermott, Ultan RA Garnett, Mathew J. RA Jenkins, Roger L. RA Rieger-Christ, Kimberly M. RA Sullivan, Travis B. RA Hezel, Aram Francis RA Liss, Andrew S. RA Mizukami, Yusuke RA Goyal, Lipika RA Ferrone, Cristina Rosa RA Zhu, Andrew Xiu-Xuan RA Joung, Jae Keith RA Shokat, Kevan Michael RA Benes, Cyril Henri RA Bardeesy, Nabeel M. RT "Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity RT and SRC dependence in intrahepatic cholangiocarcinoma."; RL Cancer Discov. 6:727-739(2016). // RX PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448; RA Vijay, Vindhya RA Karisani, Negin RA Shi, Lei RA Hung, Yu-Han RA Vu, Phuong RA Kattel, Prabhat RA Kenney, Lauren RA Merritt, Joshua RA Adil, Ramzi RA Wu, Qi-Biao RA Zhen, Yuan-Li RA Morris, Robert RA Kreuzer, Johannes RA Kathiresan, Meena RA Herrera Lopez, Xcanda Ixchel RA Ellis, Haley RA Gritti, Ilaria G. RA Lecorgne, Lilian RA Farag, Ines RA Popa, Alexandra RA Shen, William RA Kato, Hiroyuki RA Xu, Qin RA Balasooriya, Eranga Roshan RA Wu, Meng-Ju RA Chaturantabut, Saireudee RA Kelley, Robin Kate RA Cleary, James Mark RA Lawrence, Michael Scott RA Root, David E. RA Benes, Cyril Henri RA Deshpande, Vikram RA Juric, Dejan RA Sellers, William Raj RA Ferrone, Cristina Rosa RA Haas, Wilhelm RA Vazquez, Francisca RA Getz, Gad RA Bardeesy, Nabeel M. RT "Generation of a biliary tract cancer cell line atlas reveals RT molecular subtypes and therapeutic targets."; RL bioRxiv 2024:07.04.601970-07.04.601970(2024). //