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Cellosaurus PC-9/CDDP (CVCL_ZZ72)

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Cell line name PC-9/CDDP
Accession CVCL_ZZ72
Resource Identification Initiative To cite this cell line use: PC-9/CDDP (RRID:CVCL_ZZ72)
Comments Population: Chinese; Han and Japanese.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B260 (PC-9)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

PubMed=17237272; DOI=10.1158/1535-7163.MCT-06-0529
Tetsuya Oguri, Yuji Bessho, Hiroyuki Achiwa, Hiroaki Ozasa, Ken Maeno, Hiroyoshi Maeda, Shigeki Sato, Ryuzo Ueda;
MRP8/ABCC11 directly confers resistance to 5-fluorouracil.
Mol. Cancer Ther. 6:122-127(2007)

PubMed=18445659; DOI=10.1158/1535-7163.MCT-07-2088
Tetsuya Oguri, Hiroaki Ozasa, Takehiro Uemura, Yuji Bessho, Mikinori Miyazaki, Ken Maeno, Hiroyoshi Maeda, Shigeki Sato, Ryuzo Ueda;
MRP7/ABCC10 expression is a predictive biomarker for the resistance to paclitaxel in non-small cell lung cancer.
Mol. Cancer Ther. 7:1150-1155(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZZ72
Encyclopedic resources Wikidata; Q102114750
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number8