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Cellosaurus PC-9/CDDP (CVCL_ZZ72)

[Text version]
Cell line name PC-9/CDDP
Accession CVCL_ZZ72
Resource Identification Initiative To cite this cell line use: PC-9/CDDP (RRID:CVCL_ZZ72)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B260 (PC-9)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line

PubMed=17237272; DOI=10.1158/1535-7163.MCT-06-0529
Oguri T., Bessho Y., Achiwa H., Ozasa H., Maeno K., Maeda H., Sato S., Ueda R.
MRP8/ABCC11 directly confers resistance to 5-fluorouracil.
Mol. Cancer Ther. 6:122-127(2007)

PubMed=18445659; DOI=10.1158/1535-7163.MCT-07-2088
Oguri T., Ozasa H., Uemura T., Bessho Y., Miyazaki M., Maeno K., Maeda H., Sato S., Ueda R.
MRP7/ABCC10 expression is a predictive biomarker for the resistance to paclitaxel in non-small cell lung cancer.
Mol. Cancer Ther. 7:1150-1155(2008)

Cell line databases/resources cancercelllines; CVCL_ZZ72
Encyclopedic resources Wikidata; Q102114750
Entry history
Entry creation29-Oct-2020
Last entry update05-Oct-2023
Version number6