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Cellosaurus M14-CDM (CVCL_ZZ71)

[Text version]
Cell line name M14-CDM
Synonyms M14 CDM; M14-Chemically Defined Medium
Accession CVCL_ZZ71
Resource Identification Initiative To cite this cell line use: M14-CDM (RRID:CVCL_ZZ71)
Comments Group: Serum/protein free medium cell line.
Population: Caucasian.
Derived from site: Metastatic; Right buttock, hypodermis; UBERON=UBERON_0013691+UBERON_0002072.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 1787; CDKN2A; Simple; c.150+2T>C (IVS1+2T>C); ClinVar=VCV000406712; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; 1787; CDKN2A; Simple; c.455insCdel26; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Heterozygous (from parent cell line).
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1395 (M14)
Sex of cell Male
Age at sampling 33Y
Category Cancer cell line

Chee D.O., Boddie A.W. Jr., Roth J.A., Holmes E.C., Morton D.L.
Production of melanoma-associated antigen(s) by a defined malignant melanoma cell strain grown in chemically defined medium.
Cancer Res. 36:1503-1509(1976)

PubMed=6386801; DOI=10.1016/S0021-9258(18)90807-0
Bumol T.F., Walker L.E., Reisfeld R.A.
Biosynthetic studies of proteoglycans in human melanoma cells with a monoclonal antibody to a core glycoprotein of chondroitin sulfate proteoglycans.
J. Biol. Chem. 259:12733-12741(1984)

Cell line databases/resources cancercelllines; CVCL_ZZ71
Encyclopedic resources Wikidata; Q102114489
Entry history
Entry creation29-Oct-2020
Last entry update05-Oct-2023
Version number7