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Cellosaurus LNCAP-AAR (CVCL_ZX07)

[Text version]
Cell line name LNCAP-AAR
Accession CVCL_ZX07
Resource Identification Initiative To cite this cell line use: LNCAP-AAR (RRID:CVCL_ZX07)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_68639; Abiraterone acetate.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1379 (LNCaP clone FGC)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

CLPUB00570
Fernanda da Luz Efe;
Establishment and characterization of abiraterone acetate resistant prostate cancer cell line.
Thesis BSc (2019); Universidade Federal de Santa Catarina; Florianopolis; Brazil

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZX07
Encyclopedic resources Wikidata; Q102114473
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number8