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Cellosaurus LK63/A3KD (CVCL_ZV65)

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Cell line name LK63/A3KD
Synonyms LK63 EphA3-knockdown; LK63-EphA3 knockdown
Accession CVCL_ZV65
Resource Identification Initiative To cite this cell line use: LK63/A3KD (RRID:CVCL_ZV65)
Comments Knockout cell: Method=shRNA knockdown; HGNC; HGNC:3387; EPHA3.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7986 (LK63 [Melbourne])
Sex of cell Sex unspecified
Age at sampling Children
Category Cancer cell line
Publications

PubMed=27922598; DOI=10.1038/leu.2016.371
Sara Charmsaz, Fares Al-Ejeh, Trina M. Yeadon, Kirrilee J. Miller, Fiona M. Smith, Brett William Stringer, Andrew S. Moore, Fook-Thean Lee, Leanne T. Cooper, Chrysanthos Stylianou, Geoffrey Thomas Yarranton ...Show all 15 authors... , John D. Woronicz, Andrew M. Scott, Martin Lackmann, Andrew Wallace Boyd; Show fewer authors
EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia.
Leukemia 31:1779-1787(2017)

Cross-references
Encyclopedic resources Wikidata; Q98126922
Gene expression databases GEO; GSM2373802
GEO; GSM2373803
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number6