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Cellosaurus LK63 [Melbourne] (CVCL_7986)

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Cell line name LK63 [Melbourne]
Synonyms Lk63; LK-63
Accession CVCL_7986
Resource Identification Initiative To cite this cell line use: LK63 [Melbourne] (RRID:CVCL_7986)
Comments Doubling time: 13 hours (PubMed=1378917).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_ZV65 (LK63/A3KD)
Sex of cell Sex unspecified
Age at sampling Children
Category Cancer cell line
Publications

PubMed=1378917; DOI=10.1016/0145-2126(92)90016-Z
Evelyn Salvaris, Jurgen R. Novotny, Karen Welch, Lynda J. Campbell, Andrew Wallace Boyd;
Characterization of two novel pre-B-cell lines (LK63 and LiLa-1): potential models of pre-B-cell differentiation.
Leuk. Res. 16:655-663(1992)

PubMed=9067587; DOI=10.1038/sj.leu.2400571
Cord C. Uphoff, Roderick A.F. MacLeod, Sabine A. Denkmann, Todd Robert Golub, Arndt Borkhardt, Johannes W.G. Janssen, Hans Gunther Drexler;
Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.
Leukemia 11:441-447(1997)

PubMed=27922598; DOI=10.1038/leu.2016.371
Sara Charmsaz, Fares Al-Ejeh, Trina M. Yeadon, Kirrilee J. Miller, Fiona M. Smith, Brett William Stringer, Andrew S. Moore, Fook-Thean Lee, Leanne T. Cooper, Chrysanthos Stylianou, Geoffrey Thomas Yarranton ...Show all 15 authors... , John D. Woronicz, Andrew M. Scott, Martin Lackmann, Andrew Wallace Boyd; Show fewer authors
EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia.
Leukemia 31:1779-1787(2017)

Cross-references
Anatomy/cell type resources BTO; BTO_0000606
Encyclopedic resources Wikidata; Q54902673
Gene expression databases GEO; GSM2373800
GEO; GSM2373801
Polymorphism and mutation databases Cosmic; 1130240
Cosmic; 2491070
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number15