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Cellosaurus LK63 [Melbourne] (CVCL_7986)

[Text version]
Cell line name LK63 [Melbourne]
Synonyms Lk63; LK-63
Accession CVCL_7986
Resource Identification Initiative To cite this cell line use: LK63 [Melbourne] (RRID:CVCL_7986)
Comments Doubling time: 13 hours (PubMed=1378917).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_ZV65 (LK63/A3KD)
Sex of cell Sex unspecified
Age at sampling Children
Category Cancer cell line
Publications

PubMed=1378917; DOI=10.1016/0145-2126(92)90016-Z
Salvaris E., Novotny J.R., Welch K., Campbell L.J., Boyd A.W.
Characterization of two novel pre-B-cell lines (LK63 and LiLa-1): potential models of pre-B-cell differentiation.
Leuk. Res. 16:655-663(1992)

PubMed=9067587; DOI=10.1038/sj.leu.2400571
Uphoff C.C., MacLeod R.A.F., Denkmann S.A., Golub T.R., Borkhardt A., Janssen J.W.G., Drexler H.G.
Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.
Leukemia 11:441-447(1997)

PubMed=27922598; DOI=10.1038/leu.2016.371
Charmsaz S., Al-Ejeh F., Yeadon T.M., Miller K.J., Smith F.M., Stringer B.W., Moore A.S., Lee F.-T., Cooper L.T., Stylianou C., Yarranton G.T., Woronicz J., Scott A.M., Lackmann M., Boyd A.W.
EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia.
Leukemia 31:1779-1787(2017)

Cross-references
Anatomy/cell type resources BTO; BTO_0000606
Encyclopedic resources Wikidata; Q54902673
Gene expression databases GEO; GSM2373800
GEO; GSM2373801
Polymorphism and mutation databases Cosmic; 1130240
Cosmic; 2491070
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number15