Cellosaurus cell line 161MA-F (CVCL

Cellosaurus 161MA-F (CVCL_ZT84)

Cross-references
Cell line name	161MA-F
Synonyms	161 MAnchester-F
Accession	CVCL_ZT84
Resource Identification Initiative	To cite this cell line use: 161MA-F (RRID:CVCL_ZT84)
Comments	Population: Indian. Senescence: Senesces at 19 PDL (PubMed=9649131). Derived from site: In situ; Mesentery; UBERON=UBERON_0002095.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu344Pro (c.1031T>C); ClinVar=VCV000012375; Zygosity=Hemizygous (PubMed=8649785; PubMed=9649131).
Disease	Li-Fraumeni syndrome (NCIt: C3476) Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_ZT83 ! 160MA CVCL_ZT85 ! 161MA-M
Sex of cell	Male
Age at sampling	45Y
Category	Finite cell line
Publications	PubMed=8649785 Jennifer M. Varley, Gail McGown, Mary Thorncroft, Susan Cochrane, Patrick J. Morrison, Penella J. Woll, Anna M. Kelsey, Erika L.D. Mitchell, Jennifer Boyle, Jillian M. Birch, Dafydd Gareth Richard Evans; A previously undescribed mutation within the tetramerisation domain of TP53 in a family with Li-Fraumeni syndrome. Oncogene 12:2437-2442(1996) PubMed=9649131; DOI=10.1038/bjc.1998.364; PMCID=PMC2150396 John Michael Boyle, Erika L.D. Mitchell, Martin J. Greaves, Stephen A. Roberts, Katy Tricker, Emma Burt, Jennifer M. Varley, Jillian M. Birch, David Scott; Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families. Br. J. Cancer 77:2181-2192(1998)
Encyclopedic resources	Wikidata; Q98125286
Entry history
Entry creation	02-Jul-2020
Last entry update	19-Dec-2024
Version number	7