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Cellosaurus 160MA (CVCL_ZT83)

[Text version]
Cell line name 160MA
Synonyms 160 MAnchester
Accession CVCL_ZT83
Resource Identification Initiative To cite this cell line use: 160MA (RRID:CVCL_ZT83)
Comments Population: Indian.
Senescence: Senesces at 17 PDL (PubMed=9649131).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
Disease Li-Fraumeni syndrome (NCIt: C3476)
Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_ZT84 ! 161MA-F
CVCL_ZT85 ! 161MA-M
Sex of cell Male
Age at sampling 45Y
Category Finite cell line
Publications

PubMed=8649785
Varley J.M., McGown G., Thorncroft M., Cochrane S., Morrison P., Woll P.J., Kelsey A.M., Mitchell E.L.D., Boyle J., Birch J.M., Evans D.G.R.
A previously undescribed mutation within the tetramerisation domain of TP53 in a family with Li-Fraumeni syndrome.
Oncogene 12:2437-2442(1996)

PubMed=9649131; DOI=10.1038/bjc.1998.364; PMCID=PMC2150396
Boyle J.M., Mitchell E.L.D., Greaves M.J., Roberts S.A., Tricker K., Burt E., Varley J.M., Birch J.M., Scott D.
Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families.
Br. J. Cancer 77:2181-2192(1998)

Cross-references
Encyclopedic resources Wikidata; Q98125284
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number7