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Cellosaurus AT6BR (CVCL_ZN47)

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Cell line name AT6BR
Synonyms Ataxia Telangiectasia 6 BRighton
Accession CVCL_ZN47
Resource Identification Initiative To cite this cell line use: AT6BR (RRID:CVCL_ZN47)
Comments Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Arg1921Ter (c.5763-1050A>G) (IVS40+1126A>G) (5762ins137); ClinVar=VCV000003021; Zygosity=Unspecified (PubMed=12082606).
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2563 ! AT6BR LCL
Sex of cell Female
Age at sampling 13Y
Category Finite cell line
Publications

PubMed=12082606; DOI=10.1038/sj.onc.1205596
Pierre-Marie Girard, Enriqueta Riballo, Adrian C. Begg, Alastair P.W. Waugh, Penelope Ann Jeggo;
Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest.
Oncogene 21:4191-4199(2002)

PubMed=18079351; DOI=10.1259/bjr/27072321
Colin Francis Arlett, Michael H.L. Green, Paul Bryan Rogers, Alan Robert Lehmann, Piers N. Plowman;
Minimal ionizing radiation sensitivity in a large cohort of xeroderma pigmentosum fibroblasts.
Br. J. Radiol. 81:51-58(2008)

Cross-references
Encyclopedic resources Wikidata; Q98125518
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number8