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Cellosaurus AT6BR LCL (CVCL_2563)

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Cell line name AT6BR LCL
Synonyms Ataxia Telangiectasia 6 BRighton LCL; LB541; 541
Accession CVCL_2563
Resource Identification Initiative To cite this cell line use: AT6BR LCL (RRID:CVCL_2563)
Comments Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Arg1921Ter (c.5763-1050A>G) (IVS40+1126A>G) (5762ins137); ClinVar=VCV000003021; Zygosity=Unspecified (from autologous cell line AT6BR).
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_ZN47 ! AT6BR
Sex of cell Female
Age at sampling 13Y
Category Transformed cell line
Publications

PubMed=12082606; DOI=10.1038/sj.onc.1205596
Pierre-Marie Girard, Enriqueta Riballo, Adrian C. Begg, Alastair P.W. Waugh, Penelope Ann Jeggo;
Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest.
Oncogene 21:4191-4199(2002)

Cross-references
Cell line collections (Providers) ECACC; 98062326
Encyclopedic resources Wikidata; Q54902071
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number16