Cellosaurus cell line GN11-EGFP (CVCL

Cellosaurus GN11-EGFP (CVCL_ZL26)

Cross-references
Cell line name	GN11-EGFP
Synonyms	GN11-GFP
Accession	CVCL_ZL26
Resource Identification Initiative	To cite this cell line use: GN11-EGFP (RRID:CVCL_ZL26)
Comments	Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Brain, hypothalamus; UBERON=UBERON_0001898. Cell type: GnRH neuron; CL=CL_0011111.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: Transgenic with human GNRH1 promoter-Tg(SV40).
Hierarchy	Parent: CVCL_ZL25 (GN11)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=15471890; DOI=10.1093/hmg/ddh309 Anna Maria Cariboni, Federica Pimpinelli, Sophia Alison Colamarino, Roberta Zaninetti, Margherita Piccolella, Cristiano Rumio, Flavio Piva, Elena I. Rugarli, Roberto Maggi; The product of X-linked Kallmann's syndrome gene (KAL1) affects the migratory activity of gonadotropin-releasing hormone (GnRH)-producing neurons. Hum. Mol. Genet. 13:2781-2791(2004) PubMed=16207762; DOI=10.1242/dev.02033 Anna Maria Cariboni, Sonja Rakic, Anastasia Liapi, Roberto Maggi, Andre Goffinet, John G. Parnavelas; Reelin provides an inhibitory signal in the migration of gonadotropin-releasing hormone neurons. Development 132:4709-4718(2005)
Encyclopedic resources	Wikidata; Q98126645
Entry history
Entry creation	02-Jul-2020
Last entry update	14-Aug-2025
Version number	9