Cellosaurus logo
expasy logo

Cellosaurus LanthaScreen STAT5 (JAK2 V617F) U2OS (CVCL_ZJ10)

[Text version]
Cell line name LanthaScreen STAT5 (JAK2 V617F) U2OS
Accession CVCL_ZJ10
Resource Identification Initiative To cite this cell line use: LanthaScreen STAT5 (JAK2 V617F) U2OS (RRID:CVCL_ZJ10)
Comments Population: Caucasian.
Characteristics: Transfected with both a emGFP-STAT5A and a GST-JAK2(V617F) constructs whose expression are under the control of a CMV promoter.
Transfected with: HGNC; 6192; JAK2 (with p.Val617Phe).
Transfected with: HGNC; 11366; STAT5A.
Transfected with: UniProtKB; P42212; GFP (with p.Ser65Thr, p.Ser72Ala, p.Asn149Lys, p.Met153Thr, p.Ile167Thr and p.His231Leu = EmGFP).
Transfected with: UniProtKB; P33967; B.cereus Bsr.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Web pages https://www.thermofisher.com/order/catalog/product/K1588
Cross-references
Encyclopedic resources Wikidata; Q98126860
Entry history
Entry creation02-Jul-2020
Last entry update05-Oct-2023
Version number6