ID   LanthaScreen STAT5 (JAK2 V617F) U2OS
AC   CVCL_ZJ10
DR   Wikidata; Q98126860
WW   Provider; Thermo Fisher; K1588; https://www.thermofisher.com/order/catalog/product/K1588
CC   Population: Caucasian.
CC   Characteristics: Transduced with a EmGFP-STAT5A construct and transfected with a GST-JAK2(V617F) construct whose expression are under the control of a CMV promoter.
CC   Sequence variation: Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=FPbase; GLAD6; Emerald (Note=EmGFP, green fluorescent protein derived from GFP).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11366; STAT5A.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6192; JAK2 (Note=With p.Val617Phe).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 02-07-20; Last updated: 10-04-25; Version: 9
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