Cellosaurus cell line FTD3#6-iPSC (CVCL

Cellosaurus FTD3#6-iPSC (CVCL_ZI77)

[Text version]

Cell line name

FTD3#6-iPSC

Accession

CVCL_ZI77

Resource Identification Initiative

To cite this cell line use: FTD3#6-iPSC (RRID:CVCL_ZI77)

Comments

Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.

Sequence variations

Mutation; HGNC; HGNC:4601; GRN; Simple; c.-8+5G>C (IVS1+5G>C) (g-3826G>C); ClinVar=VCV000098119; Zygosity=Unspecified (PubMed=25556567).

Disease

Frontotemporal dementia (NCIt: C84719)
Behavioral variant of frontotemporal dementia (ORDO: Orphanet_275864)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_ZI78 (FTD3#6-PGRN)

Category

Induced pluripotent stem cell

Publications

PubMed=25556567; DOI=10.1016/j.stemcr.2014.12.001; PMCID=PMC4297877
Susanna Raitano, Laura Ordovas, Louis De Muynck, Wen-Ting Guo, Ira Espuny-Camacho, Martine Geraerts, Satish Khurana, Kim Vanuytsel, Balazs I. Toth, Thomas Voets, Rik Vandenberghe ...Show all 16 authors... , Toni Cathomen, Ludo Van Den Bosch, Pierre Vanderhaeghen, Philip Van Damme, Catherine M. Verfaillie; Show fewer authors
Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia.
Stem Cell Reports 4:16-24(2015)

Cross-references

Encyclopedic resources

Wikidata; Q98126272

Entry history

Entry creation

02-Jul-2020

Last entry update

10-Apr-2025

Version number