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Cellosaurus PUT (CVCL_ZI12)

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Cell line name PUT
Accession CVCL_ZI12
Resource Identification Initiative To cite this cell line use: PUT (RRID:CVCL_ZI12)
Comments Population: African; Nigerian.
Selected for resistance to: ChEBI; CHEBI_472805; Ouabain.
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr163His (c.487T>C); ClinVar=VCV000376680; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu287Ter (c.859G>T); Zygosity=Unspecified (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2676 (P3HR-1)
Children:
CVCL_ZI18 (NAMPUT)CVCL_2697 (PUTKO)CVCL_ZI17 (PUTRAL)
CVCL_6219 (RUDPUT-2)
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=6245297; DOI=10.1093/jnci/64.4.725
George Klein, Jesper Zeuthen, Ingrid Eriksson, Paul Ichiro Terasaki, Marietta Bernoco, Anders Rosen, Giuseppe Masucci, Susan Povey, Rosalie Ber;
Hybridization of a myeloid leukemia-derived human cell line (K562) with a human Burkitt's lymphoma line (P3HR-1).
J. Natl. Cancer Inst. 64:725-738(1980)

PubMed=6278187; DOI=10.1093/jnci/68.2.179
Jesper Zeuthen, George Klein, Rosalie Ber, Giuseppe Masucci, Susanne Bisballe, Susan Povey, Paul Ichiro Terasaki, Peter Ralph;
Human lymphoma-lymphoma hybrids and lymphoma-leukemia hybrids. I Isolation, characterization, cell surface markers, and B-cell markers.
J. Natl. Cancer Inst. 68:179-195(1982)

PubMed=6278188; DOI=10.1093/jnci/68.2.197
George Klein, Jesper Zeuthen, Rosalie Ber, Ingemar Ernberg;
Human lymphoma-lymphoma hybrids and lymphoma-leukemia hybrids. II Epstein-Barr virus induction patterns.
J. Natl. Cancer Inst. 68:197-202(1982)

PubMed=6811418; DOI=10.1016/S0171-2985(11)80031-8
Gad Spira, Norio Koide, Pierre Aman, Rosalie Ber, George Klein;
Truncated mu chain in a Burkitt lymphoma line (P3HR-1) and its fate in various hemapoietic somatic cell hybrids.
Immunobiology 162:199-209(1982)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZI12
Encyclopedic resources Wikidata; Q98128718
Polymorphism and mutation databases Cosmic; 1070697
Cosmic; 1071882
Cosmic; 1176614
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number10