Cellosaurus cell line 1321N1-HA-P2Y12 (CVCL

Cross-references
Cell line name	1321N1-HA-P2Y12
Accession	CVCL_ZD95
Resource Identification Initiative	To cite this cell line use: 1321N1-HA-P2Y12 (RRID:CVCL_ZD95)
Comments	Problematic cell line: Contaminated. Ancestral cell line (U-118MG) has been shown to be a U-138MG derivative. Population: Caucasian. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:18124; P2RY12 (Note=With a N-terminal HA tag). Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Mutation; HGNC; HGNC:9588; PTEN; Simple; c.1026+1G>T (IVS8+1G>T); ClinVar=VCV000635377; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Homozygous (from parent cell line).
Disease	Astrocytoma (NCIt: C60781) Astrocytoma (ORDO: Orphanet_94)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0110 (1321N1)
Sex of cell	Male
Age at sampling	47Y
Category	Cancer cell line
Cell line collections (Providers)	Kerafast; ENC023
Cell line databases/resources	cancercelllines; CVCL_ZD95
Encyclopedic resources	Wikidata; Q98125087
Entry history
Entry creation	02-Jul-2020
Last entry update	14-Aug-2025
Version number	11