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Cellosaurus 1321N1-HA-P2Y4 (CVCL_ZD92)

[Text version]
Cell line name 1321N1-HA-P2Y4
Accession CVCL_ZD92
Resource Identification Initiative To cite this cell line use: 1321N1-HA-P2Y4 (RRID:CVCL_ZD92)
Comments Problematic cell line: Contaminated. Ancestral cell line (U-118MG) has been shown to be a U-138MG derivative.
Population: Caucasian.
Transfected with: HGNC; 8542; P2RY4 (with a N-terminal HA tag).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from sampling site: Brain.
Sequence variations
  • Mutation; HGNC; 9588; PTEN; Simple; c.1026+1G>T (IVS8+1G>T); ClinVar=VCV000635377; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Homozygous (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0110 (1321N1)
Sex of cell Male
Age at sampling 47Y
Category Cancer cell line

Kennedy C., Qi A.D., Herold C.L., Harden T.K., Nicholas R.A.
ATP, an agonist at the rat P2Y(4) receptor, is an antagonist at the human P2Y(4) receptor.
Mol. Pharmacol. 57:926-931(2000)

Cell line collections Kerafast; ENC020
Encyclopedic resources Wikidata; Q98125091
Entry history
Entry creation02-Jul-2020
Last entry update21-Mar-2023
Version number6