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Cellosaurus NIH 3T3 Met-Y1228H (CVCL_ZD78)

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Cell line name NIH 3T3 Met-Y1228H
Synonyms Murine MET (Y1248H) Expressing NIH3T3 Cell Line
Accession CVCL_ZD78
Resource Identification Initiative To cite this cell line use: NIH 3T3 Met-Y1228H (RRID:CVCL_ZD78)
Comments Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:96969; Met (Note=With p.Tyr1228His).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss.
Hierarchy Parent: CVCL_0594 (NIH 3T3)
Sex of cell Male
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=9326629; DOI=10.1073/pnas.94.21.11445; PMCID=PMC23495
Michael Jeffers, Laura S. Schmidt, Noboru Nakaigawa, Craig P. Webb, Gregor Weirich, Takeshi Kishida, Berton Zbar, George F. Vande Woude Jr.;
Activating mutations for the met tyrosine kinase receptor in human cancer.
Proc. Natl. Acad. Sci. U.S.A. 94:11445-11450(1997)

PubMed=10327054; DOI=10.1038/sj.onc.1202547
Laura S. Schmidt, Kerstin Junker, Noboru Nakaigawa, Tracy Kinjerski, Gregor Weirich, Maria Miller, Irina A. Lubensky, Hartmut P.H. Neumann, Hiltrud Brauch, Johann Decker, Cathy D. Vocke ...Show all 19 authors... , James A. Brown, Robert Brian Jenkins, Stephane Richard, Ulf S.R. Bergerheim, Bernard Gerrard, Michael Dean, William Marston Linehan, Berton Zbar; Show fewer authors
Novel mutations of the MET proto-oncogene in papillary renal carcinomas.
Oncogene 18:2343-2350(1999)

Cross-references
Cell line collections (Providers) Kerafast; ENH032-FP
Encyclopedic resources Wikidata; Q98127858
Entry history
Entry creation02-Jul-2020
Last entry update14-Aug-2025
Version number7